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  2. De novo synthesis - Wikipedia

    en.wikipedia.org/wiki/De_novo_synthesis

    Cholesterol also serves as a precursor for the biosynthesis of steroid hormones, bile acid [2] and vitamin D. In mammals cholesterol is either absorbed from dietary sources or is synthesized de novo. Up to 70-80% of de novo cholesterol synthesis occurs in the liver, and about 10% of de novo cholesterol synthesis occurs in the small intestine. [3]

  3. Arginine and proline metabolism - Wikipedia

    en.wikipedia.org/wiki/Arginine_and_proline...

    Arginine and proline metabolism is one of the central pathways for the biosynthesis of the amino acids arginine and proline from glutamate. The pathways linking arginine, glutamate, and proline are bidirectional. Thus, the net utilization or production of these amino acids is highly dependent on cell type and developmental stage.

  4. Stable isotope labeling by amino acids in cell culture

    en.wikipedia.org/wiki/Stable_isotope_labeling_by...

    In contrast, the second population is fed with growth medium containing amino acids labeled with stable (non-radioactive) heavy isotopes. For example, the medium can contain arginine labeled with six carbon-13 atoms (13 C) instead of the normal carbon-12 (12 C). When the cells are growing in this medium, they incorporate the heavy arginine into ...

  5. Arginine - Wikipedia

    en.wikipedia.org/wiki/Arginine

    Only the l-arginine (symbol Arg or R) enantiomer is found naturally. [1] Arg residues are common components of proteins. It is encoded by the codons CGU, CGC, CGA, CGG, AGA, and AGG. [2] The guanidine group in arginine is the precursor for the biosynthesis of nitric oxide. [3] Like all amino acids, it is a white, water-soluble solid.

  6. Transamination - Wikipedia

    en.wikipedia.org/wiki/Transamination

    Transamination is a chemical reaction that transfers an amino group to a ketoacid to form new amino acids.This pathway is responsible for the deamination of most amino acids. This is one of the major degradation pathways which convert essential amino acids to non-essential amino acids (amino acids that can be synthesized de novo by the organism).

  7. Amino acid synthesis - Wikipedia

    en.wikipedia.org/wiki/Amino_acid_synthesis

    Amino acid biosynthesis overview. The drawn molecules are in their neutral forms and do not fully correspond to their presented names. Humans can not synthesize all of these amino acids. Amino acid biosynthesis is the set of biochemical processes (metabolic pathways) by which the amino acids are produced.

  8. Purine nucleotide cycle - Wikipedia

    en.wikipedia.org/wiki/Purine_nucleotide_cycle

    The Purine Nucleotide Cycle is a metabolic pathway in protein metabolism requiring the amino acids aspartate and glutamate. The cycle is used to regulate the levels of adenine nucleotides, in which ammonia and fumarate are generated. [2] AMP converts into IMP and the byproduct ammonia.

  9. Ribose-phosphate diphosphokinase - Wikipedia

    en.wikipedia.org/wiki/Ribose-phosphate...

    The product of this reaction, phosphoribosyl pyrophosphate (PRPP), is used in numerous biosynthesis (de novo and salvage) pathways. PRPP provides the ribose sugar in de novo synthesis of purines and pyrimidines, used in the nucleotide bases that form RNA and DNA. PRPP reacts with orotate to form orotidylate, which can be converted to uridylate ...