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Virus infections usually begin in the peripheral tissues, and can invade the mammalian system by spreading into the peripheral nervous system and more rarely the CNS. CNS is protected by effective immune responses and multi-layer barriers, but some viruses enter with high-efficiency through the bloodstream and some by directly infecting the ...
Viral encephalitis is inflammation of the brain parenchyma, called encephalitis, by a virus.The different forms of viral encephalitis are called viral encephalitides. It is the most common type of encephalitis and often occurs with viral meningitis.
Neuroinflammation is widely regarded as chronic, as opposed to acute, inflammation of the central nervous system. [5] Acute inflammation usually follows injury to the central nervous system immediately, and is characterized by inflammatory molecules, endothelial cell activation, platelet deposition, and tissue edema. [6]
Nipah virus encephalitis [1] Poliomyelitis; Progressive rubella panencephalitis, a late complication of congenital rubella syndrome; St. Louis encephalitis; Slow virus infections, which include: Acquired immunodeficiency syndrome (AIDS) Subacute sclerosing panencephalitis by Measles virus; Progressive multifocal leukoencephalopathy; Rabies ...
Causes of encephalitis include viruses such as herpes simplex virus and rabies virus as well as bacteria, fungi, or parasites. [1] [2] Other causes include autoimmune diseases and certain medications. [2] In many cases the cause remains unknown. [2] Risk factors include a weak immune system. [2]
The tick-borne encephalitis virus is known to infect a range of hosts including ruminants, birds, rodents, carnivores, horses, and humans. The disease can also be spread from animals to humans, with ruminants and dogs providing the principal source of infection for humans. [4]
It then can result in encephalitis, when inflammation of the brain, produced by infection by the virus, damages nerve cells, which affects signaling of the brain to the body. After the virus enters the body via a mosquito bite, the virus undergoes local replication at the skin site where virus entered the body. A primary spread of virus occurs ...
The inflammation of the brain tissue may also obstruct the normal flow of CSF around the brain (hydrocephalus). [3] Seizures may occur for various reasons; in children, seizures are common in the early stages of meningitis (in 30% of cases) and do not necessarily indicate an underlying cause. [ 8 ]