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  2. Postcholecystectomy syndrome - Wikipedia

    en.wikipedia.org/wiki/Postcholecystectomy_syndrome

    Postcholecystectomy syndrome (PCS) describes the presence of abdominal symptoms after a cholecystectomy (gallbladder removal). Symptoms occur in about 5 to 40 percent of patients who undergo cholecystectomy, [1] and can be transient, persistent or lifelong. [2] [3] The chronic condition is diagnosed in approximately 10% of postcholecystectomy ...

  3. Ursodeoxycholic acid - Wikipedia

    en.wikipedia.org/wiki/Ursodeoxycholic_acid

    Ursodeoxycholic acid (UDCA), also known as ursodiol, is a secondary bile acid, produced in humans and most other species from metabolism by intestinal bacteria. It is synthesized in the liver in some species, and was first identified in bile of bears of genus Ursus , from which its name derived. [ 8 ]

  4. Biliary reflux - Wikipedia

    en.wikipedia.org/wiki/Biliary_reflux

    Biliary reflux can be confused with acid reflux, also known as gastroesophageal reflux disease (GERD). While bile reflux involves fluid from the small intestine flowing into the stomach and esophagus, acid reflux is the backflow of stomach acid into the esophagus. These conditions are often related, and differentiating between the two can be ...

  5. Biliary microlithiasis - Wikipedia

    en.wikipedia.org/wiki/Biliary_microlithiasis

    Biliary microlithiasis refers to the creation of small gallstones less than 3 mm in diameter in the biliary duct or gallbladder. It has been suggested [1] as a cause of postcholecystectomy syndrome, or PCS, the symptoms of which include: Upset stomach, nausea, and vomiting. Gas, bloating, and diarrhea. Persistent pain in the upper right abdomen ...

  6. Primary sclerosing cholangitis - Wikipedia

    en.wikipedia.org/wiki/Primary_sclerosing_cholangitis

    Some experts recommend a trial of ursodeoxycholic acid (UDCA), a bile acid occurring naturally in small quantities in humans, as it has been shown to lower elevated liver enzyme numbers in patients with PSC and has proven effective in other cholestatic liver diseases. However, UDCA has yet to be shown to clearly lead to improved liver histology ...

  7. Bile acid - Wikipedia

    en.wikipedia.org/wiki/Bile_acid

    The simplest 24-carbon bile acid has two hydroxyl groups at positions 3α and 7α. This is 3α,7α-dihydroxy-5β-cholan-24-oic acid, or, as more usually known, chenodeoxycholic acid. This bile acid was first isolated from the domestic goose, from which the "cheno" portion of the name was derived (Greek: χήν = goose). The 5β in the name ...

  8. Gallstone - Wikipedia

    en.wikipedia.org/wiki/Gallstone

    The medications ursodeoxycholic acid (UDCA) and chenodeoxycholic acid (CDCA) have been used in treatment to dissolve gallstones. [ 58 ] [ 59 ] A 2013 meta-analysis concluded that UDCA or higher dietary fat content appeared to prevent formation of gallstones during weight loss. [ 41 ]

  9. Bile - Wikipedia

    en.wikipedia.org/wiki/Bile

    Cholesterol gallstones are generally treated through surgical removal of the gallbladder. However, they can sometimes be dissolved by increasing the concentration of certain naturally occurring bile acids, such as chenodeoxycholic acid and ursodeoxycholic acid. [17] [18]

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