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Pyometra or pyometritis is a uterine infection. Though it is most commonly known as a disease of the unaltered female dog, it is also a notable human disease. It is also seen in female cattle, horses, goats, sheep, swine, cats, rabbits, hamsters, ferrets, rats and guinea pigs.
Endometrial hyperplasia is a condition of excessive proliferation of the cells of the endometrium, or inner lining of the uterus.. Most cases of endometrial hyperplasia result from high levels of estrogens, combined with insufficient levels of the progesterone-like hormones which ordinarily counteract estrogen's proliferative effects on this tissue.
It was later removed from the market due to a high risk of cystic endometrial hyperplasia and uterine infection. [4] Another progestin-based drug, megestrol acetate, was also found to be effective in prevention of oestrus in female dogs, [4] but required administration at specific time intervals, making it unsuitable for feral animals. [1]
Hyperplasia of the breast – "Hyperplastic" lesions of the breast include usual ductal hyperplasia, a focal expansion of the number of cells in a terminal breast duct, and atypical ductal hyperplasia, in which a more abnormal pattern of growth is seen, and which is associated with an increased risk of developing breast cancer.
In addition, megestrol acetate was marketed for veterinary use in dogs in 1969 in the United Kingdom and in 1974 in the United States. [152] [153] [154] Progesterone was first found to be effective in the treatment of endometrial hyperplasia in 1951, [6] and progestins were first found to be effective in the treatment of endometrial cancer in ...
The Merck Veterinary Manual was first published in 1955. [1] It was based on the Merck Manual of Diagnosis and Therapy , which was first published in 1899 as a reference for physicians. [ 1 ] The first edition of the Veterinary Manual included contributions from over 200 authors, with 389 chapters divided into sections on public health ...
Cavalier King Charles Spaniel with bandaged foot A dog's injured leg. The health of dogs is a well studied area in veterinary medicine.. Dog health is viewed holistically; it encompasses many different aspects, including disease processes, genetics, and nutritional health, for example.
Uterine hyperplasia, or enlarged uterus, is a medical symptom in which the volume and size of the uterus in a female is abnormally high. It can be a symptom of medical conditions such as adenomyosis , uterine fibroids , ovarian cysts , and endometrial cancer .