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Instrumental analysis is a field of analytical chemistry that investigates analytes using scientific instruments. Block diagram of an analytical instrument showing the stimulus and measurement of response
English: Schematic representation of an HPLC unit. (1) Solvent reservoirs, (2) Solvent degasser, (3) Gradient valve, (4) Mixing vessel for delivery of the mobile phase, (5) High-pressure pump, (6) Switching valve in "inject position", (6') Switching valve in "load position", (7) Sample injection loop, (8) Pre-column (guard column), (9) Analytical column, (10) Detector (i.e. IR, UV), (11) Data ...
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When the HPLC instrument is connected to more than one detector, it is called a hyphenated LC system. [ citation needed ] Pharmaceutical applications [ 72 ] are the major users of HPLC, LC-MS and LC-MS/MS. [ 73 ] This includes drug development [ 74 ] and pharmacology, which is the scientific study of the effects of drugs and chemicals on living ...
Waters Corporation is an American publicly traded analytical laboratory instrument and software company headquartered in Milford, Massachusetts.The company employs more than 7,800 [2] people, with manufacturing facilities located in Milford, Taunton, Massachusetts; Wexford, Ireland and Wilmslow, [3] Cheshire.
Atmospheric pressure chemical ionization chamber cross section. Atmospheric pressure chemical ionization (APCI) is an ionization method used in mass spectrometry which utilizes gas-phase ion-molecule reactions at atmospheric pressure (10 5 Pa), [1] [2] commonly coupled with high-performance liquid chromatography (HPLC). [3]
A chromatography detector is a device that detects and quantifies separated compounds as they elute from the chromatographic column.These detectors are integral to various chromatographic techniques, such as gas chromatography, [1] liquid chromatography, and high-performance liquid chromatography, [2] and supercritical fluid chromatography [3] among others.
A monolithic HPLC column, or monolithic column, is a column used in high-performance liquid chromatography (HPLC). The internal structure of the monolithic column is created in such a way that many channels form inside the column. The material inside the column which separates the channels can be porous and functionalized.