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Antiretroviral drugs are used to manage HIV/AIDS. Multiple antiretroviral drugs are often combined into a single pill in order to reduce pill burden. Some of these combinations are complete single-tablet regimens; the others must be combined with additional pills to make a treatment regimen.
The management of HIV/AIDS normally includes the use of multiple antiretroviral drugs as a strategy to control HIV infection. [1] There are several classes of antiretroviral agents that act on different stages of the HIV life-cycle. The use of multiple drugs that act on different viral targets is known as highly active antiretroviral therapy ...
In 2012, the FDA approved the drug for use as pre-exposure prophylaxis (PrEP), based on growing evidence that the drug was safe and effective at preventing HIV in populations at increased risk of infection. [41] The FDA has approved two additional medications for PrEP since then, approving Descovy in 2019 and Cabotegravir (Apretude) in 2021. [4 ...
AIDS is a peer-reviewed scientific journal that is published by Lippincott Williams & Wilkins. It was established in 1987 and is an official journal of the International AIDS Society . [ 1 ] It covers all aspects of HIV and AIDS , including basic science, clinical trials , epidemiology , and social science .
AZT prophylaxis prevented more than 1000 parental and infant deaths from AIDS in the United States. [22] In the U.S. at that time, the accepted standard of care for HIV-positive mothers was known as the 076 regimen and involved five daily doses of AZT from the second trimester onwards, as well as AZT intravenously administered during labour. [23]
Examples of ARV drugs being tested for prevention include tenofovir, dapivirine (a diarylpyrimidine inhibitor of HIV reverse transcriptase) and UC-781. [14] These next-generation microbicides have received attention and support because they are based on the same ARV drugs currently used to extend the survival (and improve the quality of life ...
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Journal of Acquired Immune Deficiency Syndromes; Journal of the Association of Nurses in AIDS Care; Journal of the International AIDS Society; Journal of the International Association of Providers of AIDS Care