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Phentermine is an norepinephrine and dopamine releasing agent (NDRA) and produces stimulant, rewarding, and appetite suppressant effects. [8] [9] [10] Chemically, it is a substituted amphetamine. [11] Phentermine was approved for medical use in the United States in 1959. [3] It is available as a generic medication. [3]
Phentermine: Substituted amphetamine: Approved for weight management (short-term) 5 kilograms (11 lb) [62] Methamphetamine: Desoxyn Substituted amphetamine: Approved for weight management (short-term) Tirzepatide: Mounjaro/ Zepbound Dual GLP-1 receptor agonist and GIP agonist: Approved for weight management (chronic) [63] 18.4 percent [64]
In 1984, researchers at the University of Rochester Medical Center reported that they had performed a double-blind, controlled clinical trial comparing phentermine alone, fenfluramine alone, a combination of phentermine and fenfluramine, and placebo, for weight loss in humans. Weight loss in those receiving the fen-phen combination was ...
Phentermine and topiramate was developed by Vivus, a California pharmaceutical company. In December 2009, Vivus, Inc. submitted a new drug application (NDA) to the FDA and on 1 March 2010, Vivus, Inc. announced that the FDA accepted the NDA for review.
JPS Health Network operates John Peter Smith Hospital, which is a 573-bed [7] acute care facility in Fort Worth, Texas. John Peter Smith Hospital provides emergency services and Level 1 trauma care. The hospital is the only psychiatric emergency services site in Tarrant County. More than 5,000 babies are born each year at John Peter Smith ...
Chlorphentermine, sold under the brand names Apsedon, Desopimon, and Lucofen, is a serotonergic appetite suppressant of the amphetamine family. Developed in 1962, it is the para-chloro derivative of the better-known appetite suppressant phentermine, which is still in current use.
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