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  2. Conditioned compensatory response - Wikipedia

    en.wikipedia.org/wiki/Conditioned_compensatory...

    CR includes a heightened pain sensitivity, and decreased body temperature, and might cause discomfort, thus motivating the drug user to continue usage of the drug. This is one of several ways classical conditioning might be a factor in drug addiction and dependence. [2] In a classic experiment, Shepard Siegel conditioned rats with morphine ...

  3. Substance intoxication - Wikipedia

    en.wikipedia.org/wiki/Substance_intoxication

    Contact high is a phenomenon that occurs in otherwise sober people who experience a drug-like effect just by coming into contact with someone who is under the influence of a psychoactive drug. In a similar way to the placebo effect, a contact high may be caused by classical conditioning as well as by the physical and social setting. [8] [9]

  4. Classical conditioning - Wikipedia

    en.wikipedia.org/wiki/Classical_conditioning

    Classical conditioning occurs when a conditioned stimulus (CS) is paired with an unconditioned stimulus (US). Usually, the conditioned stimulus is a neutral stimulus (e.g., the sound of a tuning fork), the unconditioned stimulus is biologically potent (e.g., the taste of food) and the unconditioned response (UR) to the unconditioned stimulus is an unlearned reflex response (e.g., salivation).

  5. Blocking effect - Wikipedia

    en.wikipedia.org/wiki/Blocking_effect

    In Kamin's blocking effect [1] the conditioning of an association between two stimuli, a conditioned stimulus (CS) and an unconditioned stimulus (US) is impaired if, during the conditioning process, the CS is presented together with a second CS that has already been associated with the unconditioned stimulus.

  6. Cue reactivity - Wikipedia

    en.wikipedia.org/wiki/Cue_reactivity

    [4] [3] Responses to a drug cue can be physiological (e.g., sweating, salivation, brain activity), behavioral (e.g., drug seeking), or symbolic expressive (e.g., craving). [3] The clinical utility of cue reactivity is based on the conceptualization that drug cues elicit craving which is a critical factor in the maintenance and relapse to drug use.

  7. Opioid overdose - Wikipedia

    en.wikipedia.org/wiki/Opioid_overdose

    Opiate overdose symptoms and signs can be referred to as the "opioid toxidrome triad": decreased level of consciousness, pinpoint pupils and respiratory depression. Other symptoms include seizures and muscle spasms. Sometimes an opiate overdose can lead to such a decreased level of consciousness such that the person will not wake up.

  8. Self-administration - Wikipedia

    en.wikipedia.org/wiki/Self-administration

    The higher the frequency with which a test animal emits the operant behavior, the more rewarding (and addictive), the test substance is considered. Self-administration of addictive drugs has been studied using humans, [1] non-human primates, [2] mice, [3] invertebrates such as ants, and, most commonly, rats.

  9. Latent inhibition - Wikipedia

    en.wikipedia.org/wiki/Latent_inhibition

    Latent inhibition (LI) is a technical term in classical conditioning, where a familiar stimulus takes longer to acquire meaning (as a signal or conditioned stimulus) than a new stimulus. [1] The term originated with Lubow and Moore in 1973. [2]