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Cobalt therapy is the medical use of gamma rays from the radioisotope cobalt-60 to treat conditions such as cancer.Beginning in the 1950s, cobalt-60 was widely used in external beam radiotherapy (teletherapy) machines, which produced a beam of gamma rays which was directed into the patient's body to kill tumor tissue.
External beam radiation therapy (EBRT) is a form of radiotherapy that utilizes a high-energy collimated beam of ionizing radiation, from a source outside the body, to target and kill cancer cells. The radiotherapy beam is composed of particles, which are focussed in a particular direction of travel using collimators [ 1 ] .
In addition to their uses in radiography, both cobalt-60 (60 Co) and iridium-192 (192 Ir) are used in the radiotherapy of cancer. Cobalt-60 tends to be used in teletherapy units as a higher photon energy alternative to caesium-137, while iridium-192 tends to be used in a different mode of therapy, internal radiotherapy or brachytherapy.
Radiation therapy or radiotherapy (RT, RTx, or XRT) is a treatment using ionizing radiation, generally provided as part of cancer therapy to either kill or control the growth of malignant cells. It is normally delivered by a linear particle accelerator.
Radiosurgery is surgery using radiation, [1] that is, the destruction of precisely selected areas of tissue using ionizing radiation rather than excision with a blade. Like other forms of radiation therapy (also called radiotherapy), it is usually used to treat cancer.
The first treatment of a patient using the new source was carried out in London, Ontario, on 27 October 1951. In November 1951, the first Saskatoon patient, a 43-year-old mother of four, was treated for cervical cancer with a carefully calibrated dose of cobalt-60 radiation.
Radioimmunotherapy (RIT) uses an antibody labeled with a radionuclide to deliver cytotoxic radiation to a target cell. [1] It is a form of unsealed source radiotherapy.In cancer therapy, an antibody with specificity for a tumor-associated antigen is used to deliver a lethal dose of radiation to the tumor cells.
For comparison, the average background radiation in the United States is 310 mrem (3 mSv) a year. Chronic doses above 20 rem (0.2 Sv) increase the risk of cancer. Acute doses of 500 rem (5 Sv) kill half of those affected without medical treatment. [14] Chronic doses (received over a longer period of time) are less damaging than acute doses. [15]