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  2. Pituitary pars intermedia dysfunction - Wikipedia

    en.wikipedia.org/wiki/Pituitary_pars_intermedia...

    Pituitary pars intermedia dysfunction (PPID), or equine Cushing's disease, is an endocrine disease affecting the pituitary gland of horses. It is most commonly seen in older animals, [ 1 ] and is classically associated with the formation of a long, wavy coat ( hirsutism ) and chronic laminitis .

  3. List of herbs with known adverse effects - Wikipedia

    en.wikipedia.org/wiki/List_of_herbs_with_known...

    "Potentiates digitalis activity, increases coronary dilation effects of theophylline, caffeine, papaverine, sodium nitrate, adenosine and epinephrine, increase barbiturate-induced sleeping times" [3] Horse chestnut: conker tree, conker Aesculus hippocastanum: Liver toxicity, allergic reaction, anaphylaxis [3] Kava: awa, kava-kava [4] Piper ...

  4. Flunixin - Wikipedia

    en.wikipedia.org/wiki/Flunixin

    Flunixin is a nonsteroidal anti-inflammatory drug (NSAID), analgesic, and antipyretic used in horses, cattle and pigs. It is often formulated as the meglumine salt.In the United States, it is regulated by the U.S. Food and Drug Administration (FDA), and may only be lawfully distributed by order of a licensed veterinarian.

  5. Preorbital gland - Wikipedia

    en.wikipedia.org/wiki/Preorbital_gland

    Pheromone-containing secretions from the preorbital gland may serve to establish an animal's dominance (especially in preparation for breeding), [4] mark its territory, or simply to produce a pleasurable sensation to the animal. [5] Because of its critical role in scent marking, the preorbital gland is usually considered as a type of scent gland.

  6. Xylazine - Wikipedia

    en.wikipedia.org/wiki/Xylazine

    In dogs, sheep, horses, and cattle, the half-life is very short: only 1.21– 5.97 minutes. Complete elimination of the drug can take up to 23 minutes in sheep and up to 49 minutes in horses. [1] [3] In young rats the half-life is one hour. [18] Xylazine has a large volume of distribution of V d = 1.9 – 2.5 for horses, cattle, sheep, and dogs ...

  7. Equine lymphangitis - Wikipedia

    en.wikipedia.org/wiki/Equine_Lymphangitis

    The initial pain and lameness usually respond rapidly to treatment, but the swelling may persist for many weeks. In addition, once a horse has had an episode, it appears to be predisposed to recurrence, and may suffer from "filled legs" permanently – i.e. if left in a stable and relatively immobile, poor lymphatic circulation results in a ...

  8. Gossypol - Wikipedia

    en.wikipedia.org/wiki/Gossypol

    In addition to the other side effects, the WHO researchers were concerned about gossypol's toxicity: the LD 50 in primates is less than 10 times the contraceptive dose, [14] creating a small therapeutic window. This report effectively ended further studies of gossypol as a temporary contraceptive, but research into using it as an alternative to ...

  9. Polysulfated glycosaminoglycan - Wikipedia

    en.wikipedia.org/wiki/Polysulfated_glycosaminoglycan

    Signs of overdose include exacerbated side effects such as joint pain, swelling, and lameness. [ 4 ] [ 7 ] When dogs received three times the normal dose intramuscularly twice a week for 13 weeks, they had increased liver and kidney weight, as well as microscopic lesions on the liver, kidneys, and lymph nodes .