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The infection can affect any skeletal muscle, but most often infects the large muscle groups such as the quadriceps or gluteal muscles. [2] [4] [5] Pyomyositis is mainly a disease of children and was first described by Scriba in 1885. Most patients are aged 2 to 5 years, but infection may occur in any age group.
Infection - The most common infectious cause of myositis is viral infections, such as the common cold. [4] Other viruses, such as COVID-19, are also shown to be a rare cause of myositis. [6] Benign acute childhood myositis has been described in children after prodromal viral infections with different viral agents.
[1] [9] [10] This is due to a number of factors, including: overlapping symptoms (such as muscle weakness, pain, elevated CK); that delaying treatment for an inflammatory myopathy, in order to exclude potential non-inflammatory myopathies, may cause irreversible damage (although administering immunosuppressants and glucocorticosteroids to non ...
A number of different preceding viral infections have been reported, most commonly influenza A and B. The condition appears to be more prevalent during late fall, winter, and spring. [2] Other virus infections that have been linked to BACM are those caused by Parainfluenza, Coxsackievirus, Adenovirus, Echovirus, and Mycoplasma pneumonia. [1]
Polymyositis and the associated inflammatory myopathies have an associated increased risk of cancer. [3] The features they found associated with an increased risk of cancer were older age, age greater than 45, male sex, difficulty swallowing, death of skin cells, cutaneous vasculitis, rapid onset of myositis (<4 weeks), elevated creatine kinase, higher erythrocyte sedimentation rate and higher ...
Complement deficiency has historically been associated with early, severe bacterial infections among children. [5] Infection susceptibility is frequently observed. [6] C2D is linked to abnormalities in serum immunoglobulin levels, such as lower IgG2 and IgG4 levels, which could contribute to raised infection susceptibility. More than half of 40 ...
It manifests itself in children; it is the pediatric counterpart of dermatomyositis. In JDM, the body's immune system attacks blood vessels throughout the body, causing inflammation called vasculitis. In the United States, the incidence rate of JDMS is approximately 2-3 cases per million children per year. The UK incidence is believed to be ...
The main symptoms include several kinds of skin rash along with muscle weakness in both upper arms or thighs. [8] Although dermatomyositis is closely related to polymyositis and is sometimes assumed to be a complication of that disease, most patients with dermatomyositis develop skin symptoms before any muscle involvement.