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Addition of platinum-based chemotherapy drugs to chemoradiation in women with early cervical cancer seems to improve survival and reduce risk of recurrence. [ 2 ] In total, these drugs can cause a combination of more than 40 specific side effects which include neurotoxicity , which is manifested by peripheral neuropathies including polyneuropathy .
Metals in medicine are used in organic systems for diagnostic and treatment purposes. [1] Inorganic elements are also essential for organic life as cofactors in enzymes called metalloproteins . When metals are under or over-abundant in the body, equilibrium must be returned to its natural state via interventional and natural methods.
Johnson Matthey Technology Review, known as Platinum Metals Review before 2014, is a quarterly, open access, peer-reviewed scientific journal publishing reports on scientific research on the platinum group metals and related industrial developments. [1]
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They promise to provide alternatives to platinum-based drugs for anticancer therapy. [1] [2] No ruthenium anti-cancer drug has been commercialized. Since 1979, when Cisplatin entered clinical trials, there has been continuing interest in alternative metal-based drugs. [3] The leading ruthenium-based candidates are BOLD-100 and TLD-1433.
Cisplatin is administered intravenously as short-term infusion in normal saline for treatment of solid and haematological malignancies. It is used to treat various types of cancers, including sarcomas, some carcinomas (e.g., small cell lung cancer, squamous cell carcinoma of the head and neck and ovarian cancer), lymphomas, bladder cancer, cervical cancer, [9] and germ cell tumors.
Platinum is the most promising candidate among pure metals for application in DMFCs. Platinum has the highest activity toward the dissociative adsorption of methanol. However, pure Pt surfaces are poisoned by carbon monoxide, a byproduct of methanol oxidation. Researchers have focused on dispersing nanostructured catalysts on high surface area ...
The diamond model remain attested in various disciplines, with 22.2% of diamond journals in STEM and 17.1% in Medicine. Medical diamond journals are often embedded in local communities, especially in non-western countries: "It becomes apparent that local diamond OA journals are not only important in HSS, but also in medicine." [49]