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Addition of platinum-based chemotherapy drugs to chemoradiation in women with early cervical cancer seems to improve survival and reduce risk of recurrence. [ 2 ] In total, these drugs can cause a combination of more than 40 specific side effects which include neurotoxicity , which is manifested by peripheral neuropathies including polyneuropathy .
Johnson Matthey Technology Review, known as Platinum Metals Review before 2014, is a quarterly, open access, peer-reviewed scientific journal publishing reports on scientific research on the platinum group metals and related industrial developments. [1]
Metals in medicine are used in organic systems for diagnostic and treatment purposes. [1] Inorganic elements are also essential for organic life as cofactors in enzymes called metalloproteins . When metals are under or over-abundant in the body, equilibrium must be returned to its natural state via interventional and natural methods.
Cisplatin is administered intravenously as short-term infusion in normal saline for treatment of solid and haematological malignancies. It is used to treat various types of cancers, including sarcomas, some carcinomas (e.g., small cell lung cancer, squamous cell carcinoma of the head and neck and ovarian cancer), lymphomas, bladder cancer, cervical cancer, [9] and germ cell tumors.
Organoplatinum chemistry is the chemistry of organometallic compounds containing a carbon to platinum chemical bond, and the study of platinum as a catalyst in organic reactions. [ 1 ] [ 2 ] [ 3 ] Organoplatinum compounds exist in oxidation state 0 to IV, with oxidation state II most abundant.
The diamond model remain attested in various disciplines, with 22.2% of diamond journals in STEM and 17.1% in Medicine. Medical diamond journals are often embedded in local communities, especially in non-western countries: "It becomes apparent that local diamond OA journals are not only important in HSS, but also in medicine." [49]
The Swiss Medical Weekly is a peer-reviewed open access medical journal published by the SMW supporting association. It was established in 1871 as the Correspondenz-Blatt für Schweizer Aerzte, then renamed to Schweizerische Medizinische Wochenschrift, before obtaining its current title in 2001.
They promise to provide alternatives to platinum-based drugs for anticancer therapy. [1] [2] No ruthenium anti-cancer drug has been commercialized. Since 1979, when Cisplatin entered clinical trials, there has been continuing interest in alternative metal-based drugs. [3] The leading ruthenium-based candidates are BOLD-100 and TLD-1433.