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  2. List of polysubstance combinations - Wikipedia

    en.wikipedia.org/wiki/List_of_polysubstance...

    Crack cocaine: Heroin: Chocolate rock, dragon rock, eightball, moonrock, smoking gun, tar Crack cocaine: LSD: Cracid, outerlimits Cracid is a portmanteau of crack cocaine and acid [citation needed] Crack cocaine: Meth­amphetamine: Fire, twisters Crack cocaine: Nicotine: Coolie, crimmie, woolas A cigarette laced with crack [citation needed ...

  3. Recreational drug use - Wikipedia

    en.wikipedia.org/wiki/Recreational_drug_use

    According to addiction researcher Martin A. Plant, some people go through a period of self-redefinition before initiating recreational drug use. [14] They tend to view using drugs as part of a general lifestyle that involves belonging to a subculture that they associate with heightened status and the challenging of social norms. [ 14 ]

  4. Crack cocaine - Wikipedia

    en.wikipedia.org/wiki/Crack_cocaine

    Crack cocaine, commonly known simply as crack, and also known as rock, is a free base form of the stimulant cocaine that can be smoked. Crack offers a short, intense high to smokers. The Manual of Adolescent Substance Abuse Treatment calls it the most addictive form of cocaine.

  5. Fentanyl in other drugs: Why do drug dealers mix them ... - AOL

    www.aol.com/fentanyl-other-drugs-why-drug...

    In addition to the added potency, the drug has a “low cost,” which leads drug dealers to mix fentanyl with drugs like “heroin, methamphetamine and cocaine, increasing the likelihood of a ...

  6. Speedball (drug) - Wikipedia

    en.wikipedia.org/wiki/Speedball_(drug)

    Speedball, powerball, or over and under [1] is the polydrug mixture of a stimulant with a depressant, usually an opioid.The most well-known mixture used for recreational drug use is that of cocaine and heroin; however, amphetamines can also be mixed with morphine and/or fentanyl.

  7. Opioid use disorder - Wikipedia

    en.wikipedia.org/wiki/Opioid_use_disorder

    The differences in the genetic regions encoding the dopamine receptors for each individual may help to elucidate part of the risk for opioid addiction and general substance abuse. [10] Studies of the D2 Dopamine Receptor, in particular, have shown some promising results. One specific SNP is at the TaqI RFLP (rs1800497).

  8. Fentanyl - Wikipedia

    en.wikipedia.org/wiki/Fentanyl

    Fentanyl is a highly potent synthetic piperidine opioid primarily used as an analgesic.It is 30 to 50 times more potent than heroin and 100 times more potent than morphine; [11] its primary clinical utility is in pain management for cancer patients and those recovering from painful surgeries.

  9. Substance dependence - Wikipedia

    en.wikipedia.org/wiki/Substance_dependence

    Substance dependence, also known as drug dependence, is a biopsychological situation whereby an individual's functionality is dependent on the necessitated re-consumption of a psychoactive substance because of an adaptive state that has developed within the individual from psychoactive substance consumption that results in the experience of withdrawal and that necessitates the re-consumption ...

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