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Ovine pulmonary adenocarcinoma (OPA), also known as ovine pulmonary adenomatosis, or jaagsiekte, is a chronic and contagious disease of the lungs of sheep and goats. OPA is caused by a retrovirus called jaagsiekte sheep retrovirus (JSRV).
JSRV is the virus that is the cause of the contagious lung tumors in sheep called ovine pulmonary adenocarcinoma (OPA). The disease has also been called "jaagsiekte", after the Afrikaans words for "chase" (jaag) and "sickness" (siekte), to describe the respiratory distress observed in an animal out of breath from being chased, indicating the breathing difficulty experienced by infected sheep.
Nairobi sheep disease orthonairovirus (NSDV) infection; orf, also known as contagious ecthyma, contagious pustular dermatitis, infectious labial dermatitis, thistle disease, sore mouth, or scabby mouth; ovine encephalomyelitis (louping ill) ovine progressive pneumonia (OPP) ovine pulmonary adenocarcinoma
A post-mortem examination showed she had a form of lung cancer called ovine pulmonary adenocarcinoma, also known as Jaagsiekte, [18] which is a fairly common disease of sheep and is caused by the retrovirus JSRV. [19]
Enzootic nasal adenocarcinoma is a fatal, malignant neoplastic, infectious disease in sheep and goats. It is caused by the Enzootic nasal tumor virus , a retrovirus similar to Jaagsiekte sheep retrovirus , which causes a similar disease, also in sheep and goats called Ovine pulmonary adenocarcinoma (OPA). [ 1 ]
First described in 1954 by Bjorn Sigurdsson in Iceland, [6] Maedi-visna virus was the first lentivirus to be isolated and characterized, accomplished in 1957 by Sigurdsson. [6] [7] [8] Maedi (Icelandic mæði 'dyspnoea') and visna (Icelandic visna 'wasting' [9] or 'shrinking' of the spinal cord) refer to endemic sheep herd conditions that were only found to be related after Sigurdsson's work.
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The disease, enzootic nasal adenocarcinoma is common in North America and is found in sheep and goats on every continent except New Zealand and Australia. [5] There are more than 27 betaretroviruses similar to ENVT and JSRV in the ovine genome. [6] [7] In the future, research on ENTV may become important in studying viruses that cause human ...