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Luteinizing hormone (LH, also known as luteinising hormone, [1] lutropin and sometimes lutrophin [2]) is a hormone produced by gonadotropic cells in the anterior pituitary gland. The production of LH is regulated by gonadotropin-releasing hormone (GnRH) from the hypothalamus. [ 3 ]
Low levels of the hormone leptin are also seen in females with low body weight. [40] Like ghrelin, leptin signals energy balance and fat stores to the reproductive axis. [ 3 ] Decreased levels of leptin are closely related to low levels of body fat, and correlate with a slowing of GnRH pulsing.
Hypergonadotropic hypogonadism (HH), also known as primary or peripheral/gonadal hypogonadism or primary gonadal failure, is a condition which is characterized by hypogonadism which is due to an impaired response of the gonads to the gonadotropins, follicle-stimulating hormone (FSH) and luteinizing hormone (LH), and in turn a lack of sex steroid production. [1]
The body mass index (BMI) can be a great screening tool to help estimate your risk for developing certain diseases that may later contribute to dysfunction. You can use the CDC’s BMI calculator ...
The anterior portion of the pituitary gland produces luteinizing hormone (LH) and follicle-stimulating hormone (FSH), and the gonads produce estrogen and testosterone. In oviparous organisms (e.g. fish, reptiles, amphibians, birds), the HPG axis is commonly referred to as the hypothalamus-pituitary-gonadal-liver axis (HPGL-axis) in females.
Gonadorelin is an agonist of the GnRH receptor and is used to induce the secretion of the gonadotropins follicle-stimulating hormone and luteinizing hormone from the pituitary gland and to increase sex hormone production by the gonads. [7] [8]
Obesity is defined as an abnormal accumulation of body fat, usually 20% or more over an individual's ideal body weight. [1] This is often described as a body mass index (BMI) over 30. However, BMI does not account for whether the excess weight is fat or muscle, and is not a measure of body composition. [2]
3973 16867 Ensembl ENSG00000138039 ENSMUSG00000024107 UniProt P22888 P30730 RefSeq (mRNA) NM_000233 NM_013582 NM_001364898 RefSeq (protein) NP_000224 NP_038610 NP_001351827 Location (UCSC) Chr 2: 48.69 – 48.76 Mb Chr 17: 89.02 – 89.1 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse The luteinizing hormone/choriogonadotropin receptor (LHCGR), also lutropin/choriogonadotropin ...