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Side effects from excessive doses include weight loss, trouble tolerating heat, sweating, anxiety, ... T4 is a prohormone; T4 is a precursor to the hormone T3.
Desiccated thyroid extract (DTE), is thyroid gland that has been dried and powdered for medical use. [1] It is used to treat hypothyroidism, [1] but less preferred than levothyroxine. [1] It is taken by mouth. [1] Maximal effects may take up to three weeks to occur. [1] Side effects may occur from excessive doses. [1]
A major expected side-effect of radioiodine in people with Graves' disease is the development of lifelong hypothyroidism, requiring daily treatment with thyroid hormone. On occasion, some people may require more than one radioactive treatment, depending on the type of disease present, the size of the thyroid, and the initial dose administered.
Other side effects include granulocytopenia (dose dependent, which improves on cessation of the drug) and aplastic anemia, and in case of propylthiouracil, severe, fulminant liver failure. [20] Patients on these medications should see a doctor if they develop sore throat or fever. The most common side effects are rash and peripheral neuritis. [21]
Liothyronine is a manufactured form of the thyroid hormone triiodothyronine (T 3). [1] It is most commonly used to treat hypothyroidism and myxedema coma. [1] It can be taken by mouth or by injection into a vein. [1] Side effects may occur from excessive doses. [1]
[9] [16] [66] In 2007, the British Thyroid Association stated that combined T 4 and T 3 therapy carried a higher rate of side effects and no benefit over T 4 alone. [16] [67] Similarly, American guidelines discourage combination therapy due to a lack of evidence, although they acknowledge that some people feel better when receiving combination ...
Other severe side effects include liver problems and low blood cell counts. [3] Use during pregnancy may harm the baby. [3] Propylthiouracil is in the antithyroid family of medications. [4] It works by decreasing the amount of thyroid hormone produced by the thyroid gland and blocking the conversion of thyroxine (T4) to triiodothyronine (T3). [3]
Those who developed significant side effects may also have problems with propylthiouracil. [2] Thiamazole is a cyclic thiourea derivative that works by decreasing the production of thyroid hormones. [2] Thiamazole was approved for medical use in the United States in 1950. [2] It is on the World Health Organization's List of Essential Medicines.