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A sialogogue (also spelled sialagogue, ptysmagogue or ptyalagogue) is a substance, especially a medication, that increases the flow rate of saliva. [1] The definition focuses on substances that promote production or secretion of saliva (proximal causation) rather than any food that is mouthwatering (distal causation that triggers proximal causation).
It increases the production of saliva. [2] Side effects ... Pilocarpine — a similar parasympathomimetic medication for dry mouth ...
Saliva on a baby's lips. Saliva (commonly referred to as spit or drool) is an extracellular fluid produced and secreted by salivary glands in the mouth.In humans, saliva is around 99% water, plus electrolytes, mucus, white blood cells, epithelial cells (from which DNA can be extracted), enzymes (such as lipase and amylase), and antimicrobial agents (such as secretory IgA, and lysozymes).
Anticholinergics generally have antisialagogue effects (decreasing saliva production), and most produce some level of sedation, both being advantageous in surgical procedures. [8] [9] Until the beginning of the 20th century, anticholinergic drugs were widely used to treat psychiatric disorders. [10]
The ImSAIDs were discovered by scientists evaluating biological properties of the submandibular gland and saliva. Early work in this area demonstrated that the submandibular gland released a host of factors which regulate systemic inflammatory responses and modulate systemic immune and inflammatory reactions.
Somatostatin is secreted by delta cells at several locations in the digestive system, namely the pyloric antrum, the duodenum and the pancreatic islets. [14]Somatostatin released in the pyloric antrum travels via the portal venous system to the heart, then enters the systemic circulation to reach the locations where it will exert its inhibitory effects.
The moment we take a drug — whether we snort, smoke, or swallow it — our bodies begin to break it down. In the process, metabolites, or byproducts, of the drug are produced, which can linger ...
Scopolamine, also known as hyoscine, [9] or Devil's Breath, [10] is a natural or synthetically produced tropane alkaloid and anticholinergic drug that is used as a medication to treat motion sickness [11] and postoperative nausea and vomiting. [12] [1] It is also sometimes used before surgery to decrease saliva. [1]