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The human cerebellum is located at the base of the brain, with the large mass of the cerebrum above it, and the portion of the brainstem called the pons in front of it. It is separated from the overlying cerebrum by a layer of tough dura mater called the cerebellar tentorium; all of its connections with other parts of the brain travel through the pons.
Most vertebrate species have a cerebellum and one or more cerebellum-like structures, brain areas that resemble the cerebellum in terms of cytoarchitecture and neurochemistry. [80] The only cerebellum-like structure found in mammals is the dorsal cochlear nucleus (DCN), one of the two primary sensory nuclei that receive input directly from the ...
The entire pathway begins and ends in the cerebral cortex, and its entire course is the following: [2] (Motor and sensory areas of) cerebral cortex → corticopontine fibers → (ipsilateral) nuclei pontis (synapse) → pontocerebellar fibers (decussation within pons) → middle cerebellar peduncle → (contralateral) (cerebellar cortex and (collaterals) dentate nucleus of) posterior lobe of ...
The cerebellum consists of three parts, a median and two lateral, which are continuous with each other, and are substantially the same in structure. The median portion is constricted, and is called the vermis, from its annulated appearance which it owes to the transverse ridges and furrows upon it; the lateral expanded portions are named the hemispheres.
The cerebellar peduncles are three paired bundles of fibres that connect the cerebellum to the brain stem. [1] Superior cerebellar peduncle is a paired structure of white matter that connects the cerebellum to the mid-brain. Middle cerebellar peduncles connect the cerebellum to the pons and are composed entirely of centripetal fibers.
The Purkinje cell protein 4 is markedly immunoreactive in the Purkinje cells of the human cerebellum. From top to bottom 40X, 100X and 200X microscopic magnifications. The immunohistochemistry was performed based on published methods. [11] Microcircuitry of the cerebellum. Excitatory synapses are denoted by (+) and inhibitory synapses by (-).
Cerebellar degeneration is a condition in which cerebellar cells, otherwise known as neurons, become damaged and progressively weaken in the cerebellum. [1] There are two types of cerebellar degeneration; paraneoplastic cerebellar degeneration, and alcoholic or nutritional cerebellar degeneration. [2]
Nationality: Colombian and American: Alma mater: Pontificia Universidad Javeriana and Australian National University: Known for: Physiology of the cerebellum, the thalamus, Thalamocortical dysrhythmia as well as for his pioneering work on the inferior olivary nucleus, on the squid giant synapse and on human magnetoencephalography (MEG)