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The Wassermann test or Wassermann reaction (WR) [1] is an antibody test for syphilis, named after the bacteriologist August Paul von Wassermann, based on complement fixation. It was the first blood test for syphilis and the first in the nontreponemal test (NTT) category. Newer NTTs, such as the RPR and VDRL tests, have mostly
The Venereal Disease Research Laboratory test (VDRL) is a blood test for syphilis and related non-venereal treponematoses that was developed by the eponymous US laboratory. . The VDRL test is used to screen for syphilis (it has high sensitivity), whereas other, more specific tests are used to diagnose the disea
Additionally these tests may show false-negative when the patient's antibody titer is very high due to a hook effect (also called a prozone effect). Because of the issues with false positives, confirmation with a second treponemal test that is specific for T. pallidum antibodies is recommended.
Last week, the FDA approved the first at-home, over-the-counter test to detect syphilis in human blood. Completed in 15 minutes, the "First To Know Syphilis Test" works with a pinprick of blood.
The new test received FDA authorization after the company submitted data from clinical trials showing that the First To Know Syphilis Test identified a positive specimen 93.4% of the time.
US FDA approves first at-home syphilis test. August 16, 2024 at 11:12 AM ... over-the-counter test to detect syphilis antibodies in human blood in a move that could help boost screening rates for ...
The fluorescent treponemal antibody absorption (FTA-ABS) test is a diagnostic test for syphilis.Using antibodies specific for the Treponema pallidum species, such tests would be assumed to be more specific than non-treponemal testing such as VDRL but have been shown repeatedly to be sensitive but not specific for the diagnosis of neurosyphilis in cerebrospinal fluid (CSF).
There are four stages of syphilis, each with specific symptoms. In the primary stage, a person may develop sores at the site of infection, typically on the genitals, anus or mouth.
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