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Horizontal gene transfer is the primary mechanism for the spread of antibiotic resistance in bacteria, [8] [5] [9] [10] and plays an important role in the evolution of bacteria that can degrade novel compounds such as human-created pesticides [11] and in the evolution, maintenance, and transmission of virulence. [12]
This lateral gene transfer occurred also beyond the Darwinian threshold, after heredity or vertical gene transfer was established. [4] [5] "Sequence comparisons suggest recent horizontal transfer of many genes among diverse species including across the boundaries of phylogenetic "domains". Thus determining the phylogenetic history of a species ...
Horizontal or lateral gene transfer (HGT or LGT) is the transmission of portions of genomic DNA between organisms through a process decoupled from vertical inheritance.In the presence of HGT events, different fragments of the genome are the result of different evolutionary histories.
Transformation is one of three processes that lead to horizontal gene transfer, in which exogenous genetic material passes from one bacterium to another, the other two being conjugation (transfer of genetic material between two bacterial cells in direct contact) and transduction (injection of foreign DNA by a bacteriophage virus into the host ...
An example is the viral transfer of DNA from one bacterium to another and hence an example of horizontal gene transfer. [2] [3] [page needed] Transduction does not require physical contact between the cell donating the DNA and the cell receiving the DNA (which occurs in conjugation), and it is DNase resistant (transformation is susceptible to ...
It is a mechanism of horizontal gene transfer as are transformation and transduction although these two other mechanisms do not involve cell-to-cell contact. [ 4 ] Classical E. coli bacterial conjugation is often regarded as the bacterial equivalent of sexual reproduction or mating since it involves the exchange of genetic material.
Horizontal transmission is the transmission of organisms between biotic and/or abiotic members of an ecosystem that are not in a parent-progeny relationship. Because the evolutionary fate of the agent is not tied to reproductive success of the host, horizontal transmission tends to evolve virulence .
An entire gene family may also be lost, or gained through de novo gene birth, by such extensive divergence such that a gene is considered part of a new family, or by horizontal gene transfer. When the number of genes per genome remains relatively constant, this implies that genes are gained and lost at relatively same rates.