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Protozoan infections are responsible for diseases that affect many different types of organisms, including plants, animals, and some marine life. Many of the most prevalent and deadly human diseases are caused by a protozoan infection, including African sleeping sickness, amoebic dysentery, and malaria.
Adaptation to microaerobic or anaerobic environments is essential for certain lifestyles of P. aeruginosa, for example, during lung infection in cystic fibrosis and primary ciliary dyskinesia, where thick layers of lung mucus and bacterially-produced alginate surrounding mucoid bacterial cells can limit the diffusion of oxygen.
Mitochondrial disease is a group of disorders caused by mitochondrial dysfunction. Mitochondria are the organelles that generate energy for the cell and are found in every cell of the human body except red blood cells. They convert the energy of food molecules into the ATP that powers most cell functions.
Obligate aerobes need oxygen to grow. In a process known as cellular respiration, these organisms use oxygen to oxidize substrates (for example sugars and fats) and generate energy. [6] Facultative anaerobes use oxygen if it is available, but also have anaerobic methods of energy production. [7]
It is known to cause wound infections and other species of its genera are known to cause urinary tract infections. P. vulgaris was one of the three species Hauser isolated from putrefied meat and identified (1885). Over the past two decades, the genus Proteus, and in particular P. vulgaris, has undergone a number of major taxonomic revisions.
Yersinia pestis (Y. pestis; formerly Pasteurella pestis) is a gram-negative, non-motile, coccobacillus bacterium without spores that is related to both Yersinia enterocolitica and Yersinia pseudotuberculosis, the pathogen from which Y. pestis evolved [1] [2] and responsible for the Far East scarlet-like fever.
Bacillus anthracis is a gram-positive and rod-shaped bacterium that causes anthrax, a deadly disease to livestock and, occasionally, to humans. It is the only permanent pathogen within the genus Bacillus. Its infection is a type of zoonosis, as it is transmitted from animals to humans. [1]
Mycobacterium leprae was discovered in 1873 by the Norwegian physician Gerhard Armauer Hansen (1841–1912), and was the first bacterium to be identified as a cause of disease in humans. [8] It was confirmed to be a bacterium by Albert Ludwig Sigesmund Neisser who argued with Hansen over priority for the discovery. [ 59 ]