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585 Chronic renal failure; 586 Renal failure, unspecified; 587 Renal sclerosis, unspecified; 588 Disorders resulting from impaired renal function. 588.8 Other specified disorders resulting from impaired renal function. 588.81 Hyperparathyroidism, secondary, renal; 588.89 Renal tubular acidosis; 589 Small kidney of unknown cause
Renal tubular acidosis (RTA) is a medical condition that involves an accumulation of acid in the body due to a failure of the kidneys to appropriately acidify the urine. [1] In renal physiology, when blood is filtered by the kidney, the filtrate passes through the tubules of the nephron, allowing for exchange of salts, acid equivalents, and other solutes before it drains into the bladder as urine.
Proximal renal tubular acidosis (pRTA) or type 2 renal tubular acidosis (RTA) is a type of RTA caused by a failure of the proximal tubular cells to reabsorb filtered bicarbonate from the urine, leading to urinary bicarbonate wasting and subsequent acidemia. The distal intercalated cells function normally, so the acidemia is less severe than ...
Renal ultrasonography (Renal US) is the examination of one or both kidneys using medical ultrasound. Ultrasonography of the kidneys is essential in the diagnosis and management of kidney-related diseases. The kidneys are easily examined, and most pathological changes in the kidneys are distinguishable with ultrasound.
Hypoaldosteronism may result in high blood potassium and is the cause of 'type 4 renal tubular acidosis', sometimes referred to as hyperkalemic RTA or tubular hyperkalemia. However, the acidosis, if present, is often mild. It can also cause urinary sodium wasting, leading to volume depletion and hypotension.
Distal renal tubular acidosis (dRTA) is the classical form of RTA, being the first described. Distal RTA is characterized by a failure of acid secretion by the alpha intercalated cells of the distal tubule and cortical collecting duct of the distal nephron . [ 1 ]
Renal tubular epithelial cells (RTEs) line the collecting ducts and the distal and proximal tubules of the kidney. [109] They can be difficult to identify in unstained urine, as they look similar to urothelial cells and WBCs; [ 110 ] however, they are generally larger than WBCs and smaller than urothelial cells, [ 104 ] and collecting duct ...
Medullary sponge kidney is a congenital disorder of the kidneys characterized by cystic dilatation of the collecting tubules in one or both kidneys.Individuals with medullary sponge kidney are at increased risk for kidney stones and urinary tract infection (UTI).