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In females, the paramesonephric ducts give rise to the uterine tubes, uterus, and upper portion of the vagina, while the mesonephric ducts degenerate due to the absence of male androgens. In contrast, the paramesonephric ducts begin to proliferate and differentiate in a cranial-caudal progression to form the aforementioned structures.
The internal genitalia consist of two accessory ducts: mesonephric ducts (male) and paramesonephric ducts (female). The mesonephric system is the precursor to the male genitalia and the paramesonephric to the female reproductive system. [8] As development proceeds, one of the pairs of ducts develops while the other regresses.
In the female, the paramesonephric ducts persist and undergo further development. The portions which lie in the genital cord [citation needed] fuse to form the uterus and vagina. This fusion of the paramesonephric ducts begins in the third month, and the septum formed by their fused medial walls disappears from below upward.
Female Male Gonad: Ovary: Testicle: Rete ovarii: Rete testis: Paramesonephric ducts (Müllerian ducts) Fallopian tube: Appendix testis: Uterus, cervix, vagina [1] Prostatic utricle: Mesonephric ducts (Wolffian ducts) Epoophoron: Epididymis: Gartner's duct: Vas deferens: Seminal vesicle: Mesonephric tubules: Paroophoron: Paradidymis: Urogenital ...
It has been suggested that embryos with a higher expression of Dmrt1 expression develop into males while embryos with a lower expression are led to female development. [ 1 ] In the mouse gonadal primordium, the genital ridge, which forms from intermediate mesoderm, becomes morphologically distinct at E10.5.
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As a component of the female reproductive system, the cervix is derived from the two paramesonephric ducts (also called Müllerian ducts), which develop around the sixth week of embryogenesis. During development, the outer parts of the two ducts fuse, forming a single urogenital canal that will become the vagina, cervix and uterus. [14]
Paramesonephric ducts are paired ducts derived from the embryo, and for females develop into the uterus, uterine tubes, cervix and upper two-thirds of the vagina. [6] Embryogenesis of the Müllerian ducts play important roles in ensuring normal development of the female reproductive tract.