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The central dogma of molecular biology deals with the flow of genetic information within a biological system. It is often stated as "DNA makes RNA, and RNA makes protein", [1] although this is not its original meaning. It was first stated by Francis Crick in 1957, [2] [3] then published in 1958: [4] [5] The Central Dogma.
A diagram of the central dogma of molecular biology circa 1958, as reconstructed by Francis Crick in "Central Dogma of Molecular Biology", Nature, vol. 227, pp. 561 ...
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All of these processes form part of the central dogma of molecular biology, which describes the flow of genetic information in a biological system. As in DNA , genetic information in mRNA is contained in the sequence of nucleotides , which are arranged into codons consisting of three ribonucleotides each.