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An expectorant (from the Latin expectorare, to expel or banish) works by signaling the body to increase the amount or hydration of secretions, resulting in more, yet clearer, secretions and lubricating the irritated respiratory tract. [4] One mucoactive agent, guaifenesin, has anxiolytic and muscle-relaxing properties. It is commonly available ...
Terpin hydrate is an expectorant, used in the treatment of acute and chronic bronchitis, pneumonia, bronchiectasis, chronic obstructive pulmonary disease, and infectious and inflammatory diseases of the upper respiratory tract.
Benzonatate is a prescription non-opioid alternative for the symptomatic relief of cough.[7] [9] It has been found to improve cough associated with a variety of respiratory conditions including asthma, bronchitis, pneumonia, tuberculosis, pneumothorax, opioid-resistant cough in lung cancer, and emphysema.
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The same vasoconstriction action can also result in hypertension, which is a noted side effect of pseudoephedrine. Pseudoephedrine can be used either as oral or as topical decongestant . Due to its stimulating qualities, however, the oral preparation is more likely to cause adverse effects, including urinary retention .
Guaifenesin might act as an expectorant by increasing the volume and reducing the viscosity of secretions in the trachea and bronchi via stimulation of the gastric mucosa. . This stimulation leads to an increased parasympathetic activity in the respiratory tract via the so-called gastro-pulmonary reflex, although some in vitro studies suggested that it might also act directly on the ...
Spironolactone may be more effective than birth control pills in the treatment of acne, and the combination of spironolactone with a birth control pill may have greater effectiveness for acne than either alone. [85] In addition, some clinical research has found that flutamide is more effective than spironolactone in the treatment of acne. [64]
[23] [133] This enzyme is responsible for the transformation of 11-deoxycorticosterone into corticosterone and of 11-deoxycortisol into cortisol. [13] The clinical significance of this action, if any, is unclear. [23] [133] [13] Spironolactone notably does not decrease cortisol or aldosterone levels. [16] [132]
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