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Methylphosphonyl dichloride (DC) or dichloro is an organophosphorus compound. It has commercial application in oligonucleotide synthesis, [1] but is most notable as being a precursor to several chemical weapons agents. It is a white crystalline solid that melts slightly above room temperature. [2]
Methyldichlorophosphine is produced by alkylation of phosphorus trichloride with methyl iodide followed by reduction of the resulting phosphonium salt with iron powder: [2] [3] CH 3 I + PCl 3 + AlCl 3 → [CH 3 PCl 3 ] + AlCl 3 I −
Xerostomia (when given by injection) Tardive dyskinesia (As with all antipsychotic medication, patients using aripiprazole may develop the permanent neurological disorder tardive dyskinesia.) [10] [11] [12] Stroke; Transient Ischaemic Attack; Increased body temperature; Angioedema; Cardiorespiratory arrest; Cardiorespiratory failure
[2] Dimethyl methylphosphonate is a schedule 2 chemical as it may be used in the production of chemical weapons. It will react with thionyl chloride to produce methylphosphonic acid dichloride, which is used in the production of sarin and soman nerve agents. Various amines can be used to catalyse this process. [3]
Methylphosphine is the simplest organophosphorus compound with the formula CH 3 PH 2, often written MePH 2. It is a malodorous gas that condenses to a colorless liquid. It can be produced by methylation of phosphanide salts: [1] KPH 2 + MeI → MePH 2 + KI
57 °C (135 °F; 330 K) [1] at 2 mmHg Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references
BDTH 2 had been marketed under the name OSR#1 as a dietary supplement for treatment of autism. [11] The U.S. Food and Drug Administration determined that BDTH 2 is a drug rather than a supplement and issued a warning, [ 12 ] [ 13 ] resulting in its removal from the market. [ 14 ]
Titanocene Y was tested extensively in vivo; it showed promising results against xenografted human epidermoid carcinoma [17] and prostate cancer, [18] while best results are reached against breast [19] and renal-cell cancer. [20] Titanocene Y can be given in the mouse in high dosages and it shows generally mild toxicity in the form of diarrhea.