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Aniracetam (brand names Draganon, Sarpul, Ampamet, Memodrin, Referan), also known as N-anisoyl-2-pyrrolidinone, is a racetam which is sold in Europe as a prescription drug. It is not approved by the Food and Drug Administration for use in the United States as a prescription medication or dietary supplement .
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Although aniracetam and nebracetam show some affinity for muscarinic acetylcholine receptors, only nefiracetam demonstrates nanomolar interactions with neurotransmitter receptors. Modification of membrane-located mechanisms of central signal transduction is another hypothesis.
Unlike other racetams, nefiracetam shows high affinity for the GABA A receptor (IC 50) = 8.5 nM), where it is presumed to be an agonist. [6] [7] It was able to potently inhibit 80% of muscimol binding to the GABA A receptor, although it failed to displace the remaining 20% of specific muscimol binding.
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