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Structures with names 4- and 5-nitroimidazole are equivalent from the perspective of drugs since these tautomers readily interconvert. Drugs of the 5-nitro variety include metronidazole, tinidazole, nimorazole, dimetridazole, pretomanid, ornidazole, megazol, and azanidazole. Drugs based on 2-nitroimidazoles include benznidazole and azomycin. [3]
The 5-nitroimidazole drugs (metronidazole and tinidazole) are the mainstay of treatment for infection with Trichomonas vaginalis. Treatment for both the infected patient and the patient's sexual partner is recommended, even if asymptomatic. Therapy other than 5-nitroimidazole drugs is also an option, but cure rates are much lower. [26]
Common side effects include abdominal pain, headache, nausea, and weight loss. [2] There are concerns from animal studies that it may increase the risk of cancer but these concerns have not been found in human trials. [5] Nifurtimox is not recommended in pregnancy or in those with significant kidney or liver problems. [5] It is a type of ...
The most common side effects of nitrofurantoin are nausea, headache, and flatulence. Less common adverse events (occurring in less than 1% of those taking the drug) include: [9] Gastrointestinal: diarrhea, dyspepsia, abdominal pain, constipation, emesis; Neurologic: dizziness, drowsiness, amblyopia; Respiratory: acute pulmonary hypersensitivity ...
It is on the World Health Organization's List of Essential Medicines. [4] It often comes as a 50/50 mixture with oxygen. [1] Devices with a demand valve are available for self-administration. [5] The setup and maintenance is relatively expensive for developing countries. [6] [7] There are few side effects, other than vomiting, with short-term use.
There are common side effects which include headache, dizziness, and nausea. [3] Other side effects include QT prolongation. [2] Delamanid works by blocking the manufacture of mycolic acids thus destabilising the bacterial cell wall. [4] It is in the nitroimidazole class of medications. [5]
Acetic acid [2-[(5-nitro-2-thiazolyl)amino]-oxomethyl]phenyl ester is a carboxylic ester and a member of benzamides. It is functionally related to a salicylamide. Nitazoxanide [25] is the prototype member of the thiazolides, which is a drug class of structurally-related broad-spectrum antiparasitic compounds. Nitazoxanide belongs to the class ...
Nitroxoline is an antibiotic [1] that has been in use in Europe for about fifty years, and has proven to be very effective at combating biofilm infections. Nitroxoline was shown to cause a decrease in the biofilm density of P. aeruginosa infections, which would allow access to the infection by the immune system in vivo. [2]
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109 S High St #100, Columbus, OH · Directions · (614) 224-4261