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Cytochrome P450 2E1 (abbreviated CYP2E1, EC 1.14.13.n7) is a member of the cytochrome P450 mixed-function oxidase system, which is involved in the metabolism of xenobiotics in the body. This class of enzymes is divided up into a number of subcategories, including CYP1, CYP2, and CYP3, which as a group are largely responsible for the breakdown ...
For example, CYP2E1 is the gene that encodes the enzyme CYP2E1—one of the enzymes involved in paracetamol (acetaminophen) metabolism. The CYP nomenclature is the official naming convention, although occasionally CYP450 or CYP 450 is used synonymously. These names should never be used as according to the nomenclature convention (as they denote ...
Alcohol dehydrogenase [NADP+] also known as aldehyde reductase or aldo-keto reductase family 1 member A1 is an enzyme that in humans is encoded by the AKR1A1 gene. [5] [6] [7] AKR1A1 belongs to the aldo-keto reductase (AKR) superfamily.
The gene is located on chromosome 22q13.1. near two cytochrome P450 pseudogenes (CYP2D7P and CYP2D8P). [16] Among them, CYP2D7P originated from CYP2D6 in a stem lineage of great apes and humans, [17] the CYP2D8P originated from CYP2D6 in a stem lineage of Catarrhine and New World monkeys' stem lineage. [18]
Watercress is also a known inhibitor of the cytochrome P450 CYP2E1, which may result in altered drug metabolism for individuals on certain medications (e.g., chlorzoxazone). [18] Tributyltin inhibits cytochrome P450, leading to masculinization of mollusks. [19]
6. Electric Kettles. Standard kettles are fantastic. You fill it with water, put it on the stove, turn on the flame, and in a few minutes, you have boiling water. Naturally, some people couldn’t ...
6 ‘bad’ foods you should be eating for better heart health, according to dietitians. News. News. Prevention. Pancake and waffle mix recall updated to 'deadly' risk by FDA. News.
1544 13077 Ensembl ENSG00000140505 ENSMUSG00000032310 UniProt P05177 P00186 RefSeq (mRNA) NM_000761 NM_009993 RefSeq (protein) NP_000752 NP_034123 Location (UCSC) Chr 15: 74.75 – 74.76 Mb Chr 9: 57.58 – 57.59 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Cytochrome P450 1A2 (abbreviated CYP1A2), a member of the cytochrome P450 mixed-function oxidase system, is involved in the ...