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Two-point discrimination (2PD) is the ability to discern that two nearby objects touching the skin are truly two distinct points, not one. It is often tested with two sharp points during a neurological examination [ 1 ] : 632 [ 2 ] : 71 and is assumed to reflect how finely innervated an area of skin is.
Spatial discrimination is another form of Two-point discrimination in which the practitioner tests for innervation of the skin with two blunt points of a compass (drawing tool). Just with like 2PD , the patient must be able to discriminate between the two applied points.
The dorsal column–medial lemniscus pathway (DCML) (also known as the posterior column-medial lemniscus pathway (PCML) is the major sensory pathway of the central nervous system that conveys sensations of fine touch, vibration, two-point discrimination, and proprioception (body position) from the skin and joints.
It can determine how short a distance between two impressions on the skin can be distinguished. To differentiate between two points and one point of equal area (the sum of the areas of the two points equals the area of the third point), Dr. Sidney Weinstein created the three-point esthesiometer.
Two-alternative forced choice (2AFC) is a method for measuring the sensitivity of a person or animal to some particular sensory input, stimulus, through that observer's pattern of choices and response times to two versions of the sensory input.
Graphesthesia can be considered as a type of synthetic sensation as it involves a complex interaction between three neural components i.e. Tactile sensation, two point discrimination and cortical component that stores infirmation about the symbol/letter that is being traced in the skin and was learned through some previous experience.
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