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  2. Brain-derived neurotrophic factor - Wikipedia

    en.wikipedia.org/wiki/Brain-derived_neurotrophic...

    Brain-derived neurotrophic factor (BDNF), or abrineurin, [5] is a protein [6] that, in humans, is encoded by the BDNF gene. [ 7 ] [ 8 ] BDNF is a member of the neurotrophin family of growth factors, which are related to the canonical nerve growth factor (NGF), a family which also includes NT-3 and NT-4 /NT-5.

  3. Vitamin D and neurology - Wikipedia

    en.wikipedia.org/wiki/Vitamin_D_and_neurology

    A second mechanism is through the association of neurotrophic factors like nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), glial cell line-derived neurotrophic factor (GDNF). These neurotrophic factors are proteins that are involved in the growth and survival of developing neurons and they are involved in the maintenance of ...

  4. Cerebrolysin - Wikipedia

    en.wikipedia.org/wiki/Cerebrolysin

    Cerebrolysin (developmental code name FPF-1070) is an experimental mixture of enzymatically-treated peptides derived from pig brain whose constituents can include brain-derived neurotrophic factor (BDNF), glial cell line-derived neurotrophic factor (GDNF), nerve growth factor (NGF), and ciliary neurotrophic factor (CNTF).

  5. Neurotrophin - Wikipedia

    en.wikipedia.org/wiki/Neurotrophin

    According to the United States National Library of Medicine's medical subject headings, the term neurotrophin may be used as a synonym for neurotrophic factor, [5] but the term neurotrophin is more generally reserved for four structurally related factors: nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3), and neurotrophin-4 (NT-4). [6]

  6. Neurochemical - Wikipedia

    en.wikipedia.org/wiki/Neurochemical

    Neurotrophic factors are biomolecules – nearly all of which are peptides or small proteins – that support the growth, survival, and differentiation of both developing and mature neurons. [2] [3] [4] Examples of notable neurotrophic factors include: Insulin-like growth factor-1 (IGF-1) Glial cell line-derived neurotrophic factor (GDNF)

  7. Neurotrophin mimetics - Wikipedia

    en.wikipedia.org/wiki/Neurotrophin_mimetics

    Among the TrkA agonists, the small molecule gambogic amide exerts a potent neurotrophic activity decreasing apoptosis in primary hippocampal neurons. [3] The non-peptidic TrkA agonist MT2 protects neurons from Aβ amyloid-mediated death in NGF-deficient neurons [4] and talaumidin and its derivatives show neuroprotective effects, promoting neurite outgrowth in PC12 cells. [5]

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