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The anaerobic bacteria can enter the disc through the breach, causing a low virulent and slowly developing infection. Since the disc is an avascular structure, it is an ideal environment for the growth of anaerobic bacteria. Propionibacterium acnes bacteria secrete propionic acid, which can dissolve fatty bone marrow and bone.
Degenerative disc disease; Other names: Degenerative disc disorder, intervertebral disc degeneration: Degenerated disc between C5 and C6 (vertebra at the top of the picture is C2), with osteophytes anteriorly (to the left) on the lower portion of the C5 and upper portion of the C6 vertebral body.
Degenerative changes cause compression of the spinal cord. Degenerative disc disease (DDD) may trigger the pathogenesis of neurogenic claudication. [17] When intervertebral discs degenerate and change shape in DDD, the normal movements of the spine are interrupted.
Some of the common cervical spine diseases include degenerative disc disease, cervical stenosis, and cervical disc herniation. Degenerative disc disease occurs over time when the discs within each vertebra in the neck begin to fall apart and begin to disintegrate. Because each vertebra can cause pain in different areas of the body, the pain ...
Lyme radiculopathy is usually worse at night and accompanied by extreme sleep disturbance, lymphocytic meningitis with variable headache and no fever, and sometimes by facial palsy or Lyme carditis. [12] Lyme can also cause a milder, chronic radiculopathy an average of 8 months after the acute illness. [3]
Degenerative disc disease causes narrowing of the spaces. [27] Facet joints break down; Facet joints may hypertrophy [28] Compression fractures of the spine, which are common in osteoporosis [29] Synovial cysts form on the facet joints causing compression of the spinal sac of nerves (thecal sac)
Degenerative disease is the result of a continuous process based on degenerative cell changes, affecting tissues or organs, which will increasingly deteriorate over time. [ 1 ] In neurodegenerative diseases , cells of the central nervous system stop working or die via neurodegeneration .
The risk for lumbar disc disease is increased in overweight individuals because of the increased compressive force on the nucleus pulposus, and is twice as likely to occur in men. [19] [21] A 2002 study found that lifestyle factors such as night-shift work and lack of physical activity can also increase the risk of lumbar disc disease. [22]
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