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Dutasteride and finasteride are prescription drugs for treating benign prostatic hyperplasia (BPH), also called an enlarged prostate. While broadly similar and effective, they share some differences potential users should know, such as their role in hair-loss treatment.
While finasteride (the generic form of Propecia) and dutasteride (commonly sold under the brand name Avodart) are both 5 alpha-reductase inhibitors, there's one big difference between the two: The U.S. Food and Drug Administration (FDA) has approved finasteride for the treatment of hair loss and dutasteride for the treatment of benign prostatic ...
Dutasteride is more potent than finasteride in reducing DHT levels, yet only finasteride is FDA-approved for hair loss treatment. Both medications effectively combat male pattern baldness, but clinical trials show dutasteride promotes superior hair regrowth results compared to finasteride.
Dutasteride and finasteride are two popular 5alpha-reductase inhibitors that are used to treat BPH. These drugs prevent male hormones from increasing the size of your prostate.
Potency and FDA Approval: Dutasteride is more potent than finasteride, blocking more of the DHT conversion, but only finasteride is FDA-approved for treating male pattern baldness, while dutasteride is used off-label.
Dutasteride (brand name Avodart) and finasteride (brand name Procar) are medications prescribed for the treatment of an enlarged prostate (benign prostatic hyperplasia, BPH). Both dutasteride and finasteride delay the progression of an enlarged prostate gland, which improves symptoms of BPH.
Dutasteride inhibits both type I and type II 5-alpha-reductase while finasteride inhibits only the type II enzyme. As both isoenzymes are present in hair follicles, it is likely that dutasteride is more effective than finasteride.
Potency: Dutasteride is a more potent 5ARI than finasteride. It inhibits both type 1 and type 2 of the 5-alpha reductase enzyme, while finasteride primarily targets type 2. This means that dutasteride can reduce DHT levels more effectively than finasteride.
Dutasteride and Finasteride are both effective treatments for male pattern hair loss. However, Dutasteride is a more potent DHT blocker and may be more effective for those with more advanced hair loss.
The result showed that dutasteride was more effective than finasteride in all respects for the treatment of AGA. Besides, current data illustrated that the mean change from baseline in the subjects’ assessment score was significantly higher in the dutasteride than in the finasteride group.