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Fexofenadine, sold under the brand name Allegra among others, [10] is an antihistamine pharmaceutical drug used in the treatment of allergy symptoms, such as hay fever and urticaria. [ 11 ] Therapeutically, fexofenadine is a selective peripheral H 1 blocker .
The first H 1 receptor antagonists were discovered in the 1930s and were marketed in the 1940s. [22] Piperoxan was discovered in 1933 and was the first compound with antihistamine effects to be identified. [22] Piperoxan and its analogues were too toxic to be used in humans. [22]
Allergic rhinitis, of which the seasonal type is called hay fever, is a type of inflammation in the nose that occurs when the immune system overreacts to allergens in the air. [6] It is classified as a type I hypersensitivity reaction . [ 8 ]
The most common adverse effect is sedation; this "side-effect" is utilized in many OTC sleeping-aid preparations. Other common adverse effects in first-generation H 1 -antihistamines include dizziness, tinnitus , blurred vision, euphoria , incoordination, anxiety , increased appetite leading to weight gain , insomnia , tremor, nausea and ...
Bilastine is an antihistamine medication used to treat hives (), allergic rhinitis and itchy inflamed eyes (allergic conjunctivitis) caused by an allergy. [6] It is a second-generation antihistamine and takes effect by selectively inhibiting the histamine H 1 receptor, preventing these allergic reactions. [7]
Those events will scrunch teams’ 40 games into a shorter time frame, leading to more games on back-to-back days. The Fever went 13-27 in the 2023 season, finishing sixth in the Eastern ...
Doxylamine and other first-generation antihistamines are the most widely used sleep medications in the world. [6] Typical side effects of doxylamine (at recommended doses) include dizziness, drowsiness, grogginess, and dry mouth, among others. [7] [4] As an antihistamine, doxylamine is an inverse agonist of the histamine H 1 receptor.
Loratadine, sold under the brand name Claritin among others, is a medication used to treat allergies. [5] This includes allergic rhinitis (hay fever) and hives. [5] It is also available in drug combinations such as loratadine/pseudoephedrine, in which it is combined with pseudoephedrine, a nasal decongestant. [5]
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