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Through observing these changes in myoglobin-depleted mice, it is hypothesised that myoglobin function relates to increased oxygen transport to muscle, and to oxygen storage; as well, it serves as a scavenger of reactive oxygen species. [19] In humans, myoglobin is encoded by the MB gene. [20]
TMEM145 (top) vs. Myoglobin (bottom) in situ hybridization using Mus musculus. The mouse was 8 weeks old. Myoglobin does not localize to the brain, so this shows the significance of TMEM145 localization to the brain. The TMEM145 Gene is located on the plus strand of Chromosome 19 at 19q13.2. This gene spans 11,756 nucleotides and contains 15 exons.
OSMR is widely expressed across non-haematopoietic, hepatocytes, mesothelial cells, glial cells and epithelial cell types across various organs and mammary glands. [7] OSM receptor is abundantly expressed on endothelial and stromal/fibroblast cells in the lung of mice.
Myoglobin (Mb) Neuroglobin: a myoglobin-like haemprotein expressed in vertebrate brain and retina, where it is involved in neuroprotection from damage due to hypoxia or ischemia. [11] Neuroglobin belongs to a branch of the globin family that diverged early in evolution. Cytoglobin: an oxygen sensor expressed in multiple tissues. Related to ...
Hemoglobin and myoglobin are examples of hemeproteins that respectively transport and store of oxygen in mammals and in some fish. [9] Hemoglobin is a quaternary protein that occurs in the red blood cell, whereas, myoglobin is a tertiary protein found in the muscle cells of mammals. Although they might differ in location and size, their ...
Type IIx (also known as type IId), which is less dense in mitochondria and myoglobin. This is the fastest muscle type in humans. ... In laboratory house mice, ...
Heme B or haem B (also known as protoheme IX) is the most abundant heme. [1] Hemoglobin and myoglobin are examples of oxygen transport proteins that contain heme B. The peroxidase family of enzymes also contain heme B.
567 12010 Ensembl ENSG00000166710 ENSG00000273686 ENSMUSG00000060802 UniProt P61769 P01887 RefSeq (mRNA) NM_004048 NM_009735 RefSeq (protein) NP_004039 NP_033865 Location (UCSC) Chr 15: 44.71 – 44.72 Mb Chr 2: 121.98 – 121.98 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse β 2 microglobulin (B2M) is a component of MHC class I molecules. MHC class I molecules have α 1, α 2, and ...