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Cimetidine is rapidly absorbed regardless of route of administration. [7] The oral bioavailability of cimetidine is 60 to 70%. [5] [6] The onset of action of cimetidine when taken orally is 30 minutes, [8] and peak levels occur within 1 to 3 hours. [5] Cimetidine is widely distributed throughout all tissues. [7]
Cimetidine was the first drug ever to reach more than $1 billion a year in sales, thus making it the first blockbuster drug. [ 26 ] In the pharmaceutical industry, a blockbuster drug is one that achieves acceptance by prescribing physicians as a therapeutic standard for, most commonly, a highly prevalent chronic (rather than acute) condition.
The time required for 50% of a given dose of drug to be absorbed into the systemic circulation. [7] 1.0 h Absorption rate constant: The rate at which a drug enters into the body for oral and other extravascular routes.
Editor's note: Annual percentage yields shown are as of Friday, January 17, 2024, at 8:10 a.m. ET. APYs and promotional rates for some products can vary by region and are subject to change. Sources
I set a goal to transform 50 percent of my body weight into muscle within a year. So, I took Orangetheory circuit training classes three times a week, working on both strength training and cardio.
The Dallas Cowboys are shutting down CeeDee Lamb with two games remaining after their 2023 All-Pro receiver spent the second half of the season dealing with a sprained right shoulder. The team ...
Antihistamines are drugs which treat allergic rhinitis, common cold, influenza, and other allergies. [1] Typically, people take antihistamines as an inexpensive, generic (not patented) drug that can be bought without a prescription and provides relief from nasal congestion, sneezing, or hives caused by pollen, dust mites, or animal allergy with few side effects. [1]
President-elect Donald Trump complained on Friday that American flags would still be lowered to half-staff in honor of the late President Jimmy Carter during Trump's Jan. 20 inauguration.
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