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Normal thyroid levels are also seen, and occasionally also hypothyroidism, which may assist in causing goiter (though it is not the cause of the Graves' disease). Hyperthyroidism in Graves' disease is confirmed, as with any other cause of hyperthyroidism, by measuring elevated blood levels of free (unbound) T3 and T4. [citation needed]
Graves' disease is the cause of about 50% to 80% of the cases of hyperthyroidism in the United States. [ 1 ] [ 7 ] Other causes include multinodular goiter , toxic adenoma , inflammation of the thyroid , eating too much iodine , and too much synthetic thyroid hormone .
The signs and symptoms of Graves' disease generally result from the direct and indirect effects of hyperthyroidism, although they can also be caused by other thyroidal conditions, such as Graves' ophthalmopathy, goitre and pretibial myxedema. These clinical manifestations can involve virtually every system in the body.
According to the Mayo Clinic, Graves’ disease affects the thyroid gland.The autoimmune disorder causes the body to produce too much thyroid hormone, a condition called hyperthyroidism. Thyroid ...
Muscle involvement has been reported to occur in about 80% of thyrotoxic patients (see section #Epidemiology), [7] and the most common causes of hyperthyroidism are Graves’ disease, toxic multinodular goiter, and autonomously functioning thyroid adenoma. [8]
Graves' disease is an autoimmune disorder that causes the thyroid gland to overproduce its associated hormone, a condition known as hyperthyroidism. The disorder causes the patient to experience ...
Toxic multinodular goiter is the second most common cause of hyperthyroidism (after Graves' disease) in the developed world, whereas iodine deficiency is the most common cause of hypothyroidism in developing-world countries where the population is iodine-deficient. (Decreased iodine leads to decreased thyroid hormone.)
The most common type of hyperthyroidism, Graves' disease, may additionally cause eye problems (Graves' ophthalmopathy) and skin changes of the legs (pretibial myxedema). [6] Thyroid disease may also cause muscle weakness in the form of thyrotoxic myopathy , but this is constant rather than episodic.
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