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Memantine/donepezil, sold under the brand name Namzaric among others, is a fixed dose combination medication used for the treatment of dementia of the Alzheimer's type. [1] It contains memantine, as the hydrochloride, a NMDA receptor antagonist; and donepezil as the hydrochloride, an acetylcholinesterase inhibitor. [1] It is taken by mouth. [1]
[17] [18] One guideline recommends memantine or an AChE inhibitor be considered in people in the early-to-mid stage of dementia. [ 19 ] Memantine has been associated with a modest improvement; [ 20 ] with small positive effects on cognition , mood, behavior, and the ability to perform daily activities in moderate-to-severe Alzheimer's disease.
Donepezil, sold under the brand name Aricept among others, is a medication used to treat dementia of the Alzheimer's type. [5] [6] [10] It appears to result in a small benefit in mental function and ability to function. [11]
Get your tissues out: Chevy’s new Christmas commercial is here, and it might make you weep. It will certainly teach you a bit about a therapy that may help patients with Alzheimer’s disease ...
The most effective measures only briefly improved Violette's condition. Within hours, she'd resume wailing and vomiting excessively. At 5 weeks old, her pediatrician urgently referred the family ...
Children with antenatal or infantile onset usually succumb in the first few months or years of life, whereas adolescent and adult onset forms of Niemann–Pick type C have a more insidious onset and slower progression, and affected individuals may survive to the seventh decade. Adult cases of NPC are being recognized with increasing frequency.
Drug content uniformity is a requirement for all dosage forms, particularly those containing low dose highly potent drugs. To uniquely meet this requirement, thin film formulations contain uniform dispersions of drug throughout the whole manufacturing process. [ 5 ]
Posterior cortical atrophy (PCA), also called Benson's syndrome, is a rare form of dementia which is considered a visual variant or an atypical variant of Alzheimer's disease (AD). [ 1 ] [ 2 ] [ 3 ] The disease causes atrophy of the posterior part of the cerebral cortex , resulting in the progressive disruption of complex visual processing . [ 4 ]