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Menopause can be broken down into three stages, though Tang notes that menopause and perimenopause are typically grouped together. Perimenopause: Symptoms like hot flashes and mood swings start as ...
Perimenopause, on the other hand, is less widely understood, partly because of a lack of education and awareness around this transitional time and partly because its bounds are broader and squishier.
Menopause is the permanent cessation of menstruation resulting from loss of ovarian follicular activity, defined as beginning twelve months after the final natural menstrual cycle. This twelve month time point divides menopause into early and late transition periods known as 'perimenopause' and 'postmenopause'. [4]
Fezolinetant, sold under the brand name Veozah among others, is a medication used for the treatment of hot flashes (vasomotor symptoms) due to menopause. [3] [9] It is a small-molecule, orally active, selective neurokinin-3 (NK 3) receptor antagonist which is under development by for the treatment of sex hormone-related disorders.
Hormonal therapies to reduce or stop menstrual bleeding have long been used to manage a number of gynecologic conditions including menstrual cramps (dysmenorrhea), heavy menstrual bleeding, irregular or other abnormal uterine bleeding, menstrual-related mood changes (premenstrual syndrome or premenstrual dysphoric disorder), and pelvic pain due to endometriosis or uterine fibroids.
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The antimalarial drug quinine is a traditional treatment that may be slightly effective for reducing the number of cramps, the intensity of cramps, and the number of days a person experiences cramps. Quinine has not been shown to reduce the duration (length) of a muscle cramp. [6] Quinine treatment may lead to haematologic and cardiac toxicity.
Menopause, also known as the climacteric, is the time when menstrual periods permanently stop, marking the end of reproduction. [1] [6] [7] It typically occurs between the ages of 45 and 55, although the exact timing can vary. [8] Menopause is usually a natural change related to a decrease in circulating blood estrogen levels. [3]
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