Search results
Results from the WOW.Com Content Network
cSLE, Juvenile-onset systemic lupus erythematosus, juvenile systemic lupus erythematosus, and pediatric systemic lupus erythematosus: Specialty: Rheumatology: Usual onset: Children up to 17 years old: Types: Early-onset SLE is a type of cSLE that occurs in children up to 5 years old. It tends to be more severe than cSLE in older children. Causes
Lupus nephritis is an inflammation of the kidneys caused by systemic lupus erythematosus (SLE) and childhood-onset systemic lupus erythematosus which is a more severe form of SLE that develops in children up to 18 years old; both are autoimmune diseases. [3] [4] It is a type of glomerulonephritis in which the glomeruli become inflamed.
SLE can cause pleuritic pain as well as inflammation of the pleurae known as pleurisy, which can rarely give rise to shrinking lung syndrome involving a reduced lung volume. [31] [32] Other associated lung conditions include pneumonitis, chronic diffuse interstitial lung disease, pulmonary hypertension, pulmonary emboli, and pulmonary hemorrhage.
Cancer cells can also cause defects in the cellular pathways of apoptosis (programmed cell death). As most chemotherapy drugs kill cancer cells in this manner, defective apoptosis allows survival of these cells, making them resistant. Many chemotherapy drugs also cause DNA damage, which can be repaired by enzymes in the cell that carry out DNA ...
Almost everyone with lupus has joint pain and swelling. Some develop arthritis. Frequently affected joints are the fingers, hands, wrists, and knees. [2] Other common symptoms include: chest pain during respiration; joint pain (stiffness and swelling) painless oral ulcer; fatigue; weight loss; headaches; fever with no other cause
Signs and symptoms can take as long as 14 days after exposure to appear. [2] They may include signs and symptoms commonly associated with hypersensitivity or infections. Common symptoms include: rashes and redness. [3] itching and urticaria. [2] joint pain , especially in finger and toe joints. [2] [3] fever, usually appears before rash.
Get AOL Mail for FREE! Manage your email like never before with travel, photo & document views. Personalize your inbox with themes & tabs. You've Got Mail!
Macrophage activation syndrome is a severe, potentially life-threatening, complication of several chronic rheumatic diseases of childhood. It occurs most commonly with systemic-onset juvenile idiopathic arthritis (SoJIA).