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  2. Hereditary haemochromatosis - Wikipedia

    en.wikipedia.org/wiki/Hereditary_haemochromatosis

    A study of 3,011 unrelated white Australians found that 14% were heterozygous carriers of an HFE mutation, 0.5% were homozygous for an HFE mutation, and only 0.25% of the study population had clinically relevant iron overload. Most patients who are homozygous for HFE mutations do not manifest clinically relevant haemochromatosis (see Genetics ...

  3. Haemochromatosis type 3 - Wikipedia

    en.wikipedia.org/wiki/Haemochromatosis_type_3

    Majority of the cases of hemochromatosis are caused by mutations in the HFE (Homeostatic Iron Regulator) gene. [17] Type 3 HH is characterized by compound heterozygote mutations in both transferrin receptor 2 (TFR2) and HFE, i.e. a single mutation in each gene. HFE is located on chromosome 6 and TFR2 is located on chromosome 7.

  4. Compound heterozygosity - Wikipedia

    en.wikipedia.org/wiki/Compound_heterozygosity

    Clinically, most cases of hemochromatosis are found in homozygotes for the most common mutation in the HFE gene. [1] But at each gene locus associated with the disease, there is the possibility of compound heterozygosity, often caused by inheritance of two unrelated alleles, of which one is a common or classic mutation, while the other is a ...

  5. HFE (gene) - Wikipedia

    en.wikipedia.org/wiki/HFE_(gene)

    Human homeostatic iron regulator protein, also known as the HFE protein (High FE2+), is a transmembrane protein that in humans is encoded by the HFE gene. The HFE gene is located on short arm of chromosome 6 at location 6p22.2 [ 5 ]

  6. Today’s NYT ‘Strands’ Hints, Spangram and Answers for ...

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    We'll cover exactly how to play Strands, hints for today's spangram and all of the answers for Strands #286 on Saturday, December 14. Related: 16 Games Like Wordle To Give You Your Word Game Fix ...

  7. Today's Wordle Hint, Answer for #1272 on Thursday, December ...

    www.aol.com/todays-wordle-hint-answer-1272...

    SPOILERS BELOW—do not scroll any further if you don't want the answer revealed. The New York Times. Today's Wordle Answer for #1272 on Thursday, December 12, 2024.

  8. Hemojuvelin - Wikipedia

    en.wikipedia.org/wiki/Hemojuvelin

    Hemojuvelin (HJV), also known as repulsive guidance molecule C (RGMc) or hemochromatosis type 2 protein (HFE2), is a membrane-bound and soluble protein in mammals that is responsible for the iron overload condition known as juvenile hemochromatosis in humans, a severe form of hemochromatosis.

  9. Savings interest rates today: Don't let your money hibernate ...

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    The unemployment rate edged up moderately to 4.2% from October's 4.1%. ... See our guide to the five smartest moves to make with your $10,000. What is compound interest?

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