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  2. Elimination reaction - Wikipedia

    en.wikipedia.org/wiki/Elimination_reaction

    Elimination reaction of cyclohexanol to cyclohexene with sulfuric acid and heat [1] An elimination reaction is a type of organic reaction in which two substituents are removed from a molecule in either a one- or two-step mechanism. [2] The one-step mechanism is known as the E2 reaction, and the two-step mechanism is known as the E1 reaction ...

  3. Zaytsev's rule - Wikipedia

    en.wikipedia.org/wiki/Zaytsev's_rule

    In E2 elimination reactions, a base abstracts a proton that is beta to a leaving group, such as a halide. The removal of the proton and the loss of the leaving group occur in a single, concerted step to form a new double bond.

  4. Arrow pushing - Wikipedia

    en.wikipedia.org/wiki/Arrow_pushing

    Arrow pushing or electron pushing is a technique used to describe the progression of organic chemistry reaction mechanisms. [1] It was first developed by Sir Robert Robinson.In using arrow pushing, "curved arrows" or "curly arrows" are drawn on the structural formulae of reactants in a chemical equation to show the reaction mechanism.

  5. Activation strain model - Wikipedia

    en.wikipedia.org/wiki/Activation_strain_model

    The activation strain model was originally proposed and has been extensively developed by Bickelhaupt and coworkers. [4] This model breaks the potential energy curve as a function of reaction coordinate, ζ, of a reaction into 2 components as shown in equation 1: the energy due to straining the original reactant molecules (∆E strain) and the energy due to interaction between reactant ...

  6. Anti-periplanar - Wikipedia

    en.wikipedia.org/wiki/Anti-periplanar

    This serves to weaken C-H and C-X bond, both of which are broken in an E 2 reaction. It also sets up the molecule to more easily move its σ C-H electrons into a π C-C orbital (Figure 10). Figure 8: In an E 2 mechanism, the breaking C–H bond and the leaving group are often anti-periplanar.

  7. 2-Chlorobutane - Wikipedia

    en.wikipedia.org/wiki/2-Chlorobutane

    In an E2 mechanism, a strong base (e.g. sodium hydroxide) abstracts a beta hydrogen, causing the elections from the former carbon-hydrogen bond to re-form the double bond. This action removes the leaving group, converting 2-chlorobutane to 2-butene or 1-butene depending on which beta hydrogen is removed, [ 3 ] because of Zaitsev's rule , the ...

  8. Reaction coordinate - Wikipedia

    en.wikipedia.org/wiki/Reaction_coordinate

    For a catalyzed reaction, the activation energy is lower. In chemistry, a reaction coordinate [1] is an abstract one-dimensional coordinate chosen to represent progress along a reaction pathway. Where possible it is usually a geometric parameter that changes during the conversion of one or more molecular entities, such as bond length or bond angle.

  9. Evelyn effect - Wikipedia

    en.wikipedia.org/wiki/Evelyn_effect

    There are two types of elimination reactions, E1 and E2. An E2 reaction is a One step mechanism in which carbon-hydrogen and carbon-halogen bonds break to form a double bond. C=C Pi bond. An E1 reaction is the Ionization of the carbon-halogen bond breaking to give a carbocation intermediate, then the Deprotonation of the carbocation.