Search results
Results from the WOW.Com Content Network
Dexmedetomidine, sold under the brand name Precedex among others, is a medication used for sedation. [4] Veterinarians use dexmedetomidine for similar purposes in treating cats, dogs, and horses. [ 10 ] [ 11 ] It is also used in humans to treat acute agitation associated with schizophrenia or bipolar disorder . [ 5 ]
Minimum alveolar concentration or MAC is the concentration, often expressed as a percentage by volume, of a vapour in the alveoli of the lungs that is needed to prevent movement (motor response) in 50% of subjects in response to surgical (pain) stimulus.
In the European Union, dexmedetomidine received a marketing authorization from the European Medicines Agency (EMA) on August 10, 2012, under the brand name of Dexdor. [30] It is indicated for sedation in the ICU for patients needing mechanical ventilation.
They are mainly used in research, having found limited clinical application in human medicine. They are extensively used in veterinary medicine to reverse the effects of alpha-2 agonist drugs used as sedatives, like xylazine, medetomidine and dexmedetomidine. Alpha-2 blockers increase noradrenaline release.
The dose range advised by the manufacturers is 20–40 μg/kg intravenous for moderate sedation, but this dose may need to be higher if given intramuscularly. When given intravenously, detomidine usually takes effect in 2–5 minutes, and recovery is full within 30–60 minutes.
The equation used to calculate this minimal work was derived from the work of Otis et.al. [14] and published and discussed in Grodins and Yamashiro as early as 1977. [15] In the ASV mode, every breath is synchronized with patient effort if such an effort exists, and otherwise, full mechanical ventilation is provided to the patient.
Chile has been hit by its most severe respiratory syncytial virus (RSV) outbreak in years, killing four infants and putting strain on pediatric intensive care unit (ICU) capacity. Yessenia Sanchez ...
Targeted temperature management (TTM), previously known as therapeutic hypothermia or protective hypothermia, is an active treatment that tries to achieve and maintain a specific body temperature in a person for a specific duration of time in an effort to improve health outcomes during recovery after a period of stopped blood flow to the brain. [1]