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Dexmedetomidine, sold under the brand name Precedex among others, is a medication used for sedation. [4] Veterinarians use dexmedetomidine for similar purposes in treating cats, dogs, and horses. [ 10 ] [ 11 ] It is also used in humans to treat acute agitation associated with schizophrenia or bipolar disorder . [ 5 ]
In the European Union, dexmedetomidine received a marketing authorization from the European Medicines Agency (EMA) on August 10, 2012, under the brand name of Dexdor. [30] It is indicated for sedation in the ICU for patients needing mechanical ventilation.
Detomidine is a sedative with analgesic properties. [3] α2-adrenergic agonists produce dose-dependent sedative and analgesic effects, mediated by activation of α2 catecholamine receptors, thus inducing a negative feedback response, reducing production of excitatory neurotransmitters.
Arkansas said it ran out of ICU beds for COVID-19 patients for the first time since the pandemic began. Nearly 80% of the country's ICU beds — or about 68,000 — were in use Thursday, according ...
Medetomidine is a racemic mixture of two optical or stereoisomers, levomedetomidine and dexmedetomidine. [4] The latter causes the alpha 2- adrenergic agonist effects. [5] It is often used as the hydrochloride salt, medetomidine hydrochloride, a crystalline white solid that can be administered as an intravenous drug solution with sterile water.
Jan 19, 2025; Atlanta, GA, USA; The College Football Playoff National Championship trophy at a press conference at The Westin Peachtree Plaza, Savannah Ballroom.
They are mainly used in research, having found limited clinical application in human medicine. They are extensively used in veterinary medicine to reverse the effects of alpha-2 agonist drugs used as sedatives, like xylazine, medetomidine and dexmedetomidine. Alpha-2 blockers increase noradrenaline release.
Ben Tarver’s night terrors were the first symptoms of Anti-NMDA Receptor Encephalitis, a rare autoimmune disorder that landed him in the ICU 29-Year-Old in ‘Catatonic State’ After Rare ...