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Deracoxib is a coxib class nonsteroidal anti-inflammatory drug (NSAID). [3] Like other NSAIDs, its effects are caused by inhibition of cyclooxygenase (COX) enzymes. [7] At the doses used to treat dogs, deracoxib causes greater inhibition of COX-2 than of COX-1, [3] but at doses twice those recommended for use in dogs, deracoxib significantly inhibits COX-1 as well.
In most cases, appropriate treatment protocols cause few side effects, but white blood cell counts must be monitored. Allogeneic and autologous stem cell transplantations (as is commonly done in humans) have recently been shown to be a possible treatment option for dogs. [19] Most of the basic research on transplantation biology was generated ...
Mast cell tumor on lip of a dog. Veterinary oncology is a subspecialty of veterinary medicine that deals with cancer diagnosis and treatment in animals. Cancer is a major cause of death in pet animals. In one study, 45% of the dogs that reached 10 years of age or older died of cancer. [1]
It is estimated that 1 in 3 domestic dogs will develop cancer, which is the same incidence of cancer among humans. [2] Dogs can develop a variety of cancers and most are very similar to those found in humans. Dogs can develop carcinomas of epithelial cells and organs, sarcomas of connective tissues and bones, and lymphomas or leukemias of the ...
Ovarian cancer* is uncommon in dogs, with the most common type being the granulosa cell tumor. This type of tumor can metastasize and can cause cystic endometrial hyperplasia. [165] Uterine cancer* is very rare in dogs. The most common type is benign leiomyoma. [165] Bladder cancer* is usually malignant in dogs.
Overall, the risk of developing colorectal cancer over a 10-year period was 1.98% among participants who used aspirin regularly, compared with 2.95% for people who didn’t use aspirin regularly.
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Side effects from intra-articular administration can include joint pain, swelling, lameness, and, rarely, infection of the joint. Intramuscular injection can cause dose-dependent inflammation and bleeding, since PSGAG is an analogue of the anticoagulant heparin. [4] In dogs, this may manifest as bleeding from the nose or as bloody stools. [7]