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Azithromycin causes QT prolongation that may cause life-threatening arrhythmias such as torsades de pointes. [11] No harm has been found with its use during pregnancy. [10] Its safety during breastfeeding is not confirmed, but it is likely safe. [12] Azithromycin is an azalide, a type of macrolide antibiotic. [10]
However, not all of them are safe to use during pregnancy. One of the components of bismuth subsalicylate is salicylate, which is a component that crosses the placenta. Due to this, there is an increased risk for intrauterine growth retardation, fetal hemorrhage, and maternal hemorrhage within organogenesis and in the second/third trimester. [ 12 ]
Its use later on during pregnancy also increases the risk of preterm labour (odds ratio: 1.51) and low birth weight (odds ratio: 1.67). [17] [18] Animal studies have yielded similarly discouraging results. [3] It appears to be safe for use during breastfeeding as long as the baby is healthy. [19]
Chlamydia can be cured by antibiotics, with typically either azithromycin or doxycycline being used. [2] Erythromycin or azithromycin is recommended in babies and during pregnancy. [2] Sexual partners should also be treated, and infected people should be advised not to have sex for seven days and until symptom free. [2]
Potential toxicity to mother and fetus during pregnancy; Enamel hypoplasia (staining of teeth; potentially permanent) Transient depression of bone growth; Inhibits the binding of aminoacyl-tRNA to the mRNA-ribosome complex. They do so mainly by binding to the 30S ribosomal subunit in the mRNA translation complex. But Tetracycline cannot be ...
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Erythromycin also appears to be safe to use during pregnancy. [2] While generally regarded as safe during breastfeeding, its use by the mother during the first two weeks of life may increase the risk of pyloric stenosis in the baby. [5] [6] This risk also applies if taken directly by the baby during this age. [7]
It appears to be relatively safe during pregnancy. [7] It is in the third-generation cephalosporin class of medications. [5] It works by disrupting the bacteria's cell wall resulting in its death. [5] Cefixime was patented in 1979 and approved for medical use in the United States in 1989.
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