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Serious side effects may include decreased survival in those with heart failure, low platelets, and low white blood cells. [2] Cilostazol is a phosphodiesterase 3 inhibitor which works by inhibiting platelet aggregation and dilating arteries. [2] Cilostazol was approved for medical use in the United States in 1999. [2]
Cilostazol is used for the treatment of intermittent claudication. This drug has a much weaker positive inotropic effect than those drugs used for the therapy of acute heart failure, and lacks significant adverse cardiac effects.
Frunevetmab, sold under the brand name Solensia, is a monoclonal antibody used to treat pain associated with osteoarthritis in cats. [3] It is the first monoclonal antibody drug approved by the US Food and Drug Administration for animal use. [3] Frunevetmab is the international nonproprietary name. [5]
Lentigo in cats is a common dermatological condition characterized by the presence of small, flat, brownish spots on the skin — particularly around the lips, nose, and eyelid margins. Unlike in ...
Conservative treatment of arterial thromboembolism in cats is also based on this endogenous dissolution of the clot (see below). In cats, the blood clots originate mainly in the left atrial auricle. [8] They or parts of them are carried along with the blood flow, enter the aorta via the left ventricle, get stuck at vascular outlets and block them.
Whereas PDE4C is expressed primarily in the periphery and hence may be partly responsible for the peripheral effects of PDE4 inhibitors (e.g. their anti-inflammatory effects). [14] PDE4 inhibition is also known to attenuate ethanol seeking and consumption in rats, [17] hence suggesting its possible utility in the treatment of alcohol dependence.
Lysine is commonly used as a treatment; however, in a 2015 systematic review, the authors investigated all clinical trials with cats as well as in vitro studies and concluded that lysine supplementation is likely not effective for the treatment or prevention of feline herpesvirus 1 infection. [15]
The most serious side effects associated with ticlopidine are those that affect the blood cells, although these life-threatening complications are relatively rare. The most common side effects include: [1] Diarrhea; Nausea; Dyspepsia; Rash; Abdominal pain; Ticlopidine may also cause an increase in cholesterol, triglycerides, liver enzymes, and ...