Search results
Results from the WOW.Com Content Network
[19] [31] For drugs recently sold on the market, drugs have information pages (monographs) that provide information on any potential interaction between a medication and grapefruit juice. [19] Because there is a growing number of medications that are known to interact with citrus, [ 1 ] patients should consult a pharmacist or physician before ...
Blood pressure drugs aren't the only commonly prescribed medications that grapefruit juice can mess with — they also include anticoagulants that help prevent blood clots, organ-transplant ...
When two drugs affect each other, it is a drug–drug interaction (DDI). The risk of a DDI increases with the number of drugs used. [1] A large share of elderly people regularly use five or more medications or supplements, with a significant risk of side-effects from drug–drug interactions. [2] Drug interactions can be of three kinds:
Grapefruit and grapefruit juice have been found to interact with numerous drugs, in many cases resulting in adverse effects. [4] This happens in two ways: one is that grapefruit can block an enzyme which metabolizes medication, [5] and if the drug is not metabolized, then the level of the drug in the blood can become too high, leading to an adverse effect. [5]
Unlike orange juice, grapefruit juice can impact how Cialis is metabolized in your body, leading to increased levels of the medication in your system. That can be dangerous for a variety of reasons.
The initial publication in 2002, which has been cited more than 100 times, supported a new model of intestinal drug absorption and novel mechanism of food-drug interactions. [7] Bailey showed that the major flavonoid in grapefruit, naringin , was an important clinically active inhibitor of intestinal OATP1A2.
For premium support please call: 800-290-4726 more ways to reach us
A single report has been made of grapefruit juice possibly increasing the effects of cilostazol; [9] some drug information sources list this as a possible interaction. [10] [11] [12] The FDA-approved labeling of cilostazol notes that grapefruit juice (which is a CYP3A4 inhibitor) increases the drug's maximum concentration by around 50%. [7]