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Prolactin-induced protein has also been used for identification and detection of disseminated breast cancer cells. [20] The PIP gene is amplified in some breast cancer lines accounting for some of its overexpression, however additional mechanisms are needed to completely explain its overexpression. [21]
Pokemon is the name given to the protein product of Zbtb7 gene by the research team at Memorial Sloan Kettering Cancer Center (MSKCC), which discovered its oncogenic function. It stands for " POK e rythroid m yeloid on togenic [ sic ] [ 13 ] factor" and is most likely a backronym of the Pokémon media franchise .
Scientists study the behaviour of isolated cells grown in the laboratory for insights into how cells function in the body in health and disease. Experiments using cell culture are used for developing new diagnostic tests and new treatments for diseases. This is a list of major breast cancer cell lines that are primarily used in breast cancer ...
For instance, breast cancer cells look the same whether they are found in the breast or have spread to another part of the body. So, if a tissue sample taken from a tumor in the lung contains cells that look like breast cells, the doctor determines that the lung tumor is a secondary tumor.
Fluid produced by the cells can produce ascites which is typical in carcinomatosis, but less common in peritoneal sarcomatosis. [1] Fluid can be serous as seen in primary peritoneal carcinoma or mucinous such as found in pseudomyxoma peritonei which is typically a tumor derived from the appendix .
Disseminated disease can refer to disseminated cancer which is the movement of cancerous cells from the original tumor to other areas of the body, [1] or disseminated infection which is the pathogen's entry into the host, growth, and dissemination, which results in illness. [2] After exiting the main tumor, cancer cells circulate throughout the ...
T cells must replicate after arriving at the tumor site to effectively kill the cancer cells, survive hostile elements and migrate through the stroma to the cancer cells. This is affected by the tumor microenvironment. The draining lymph nodes are the likely location for cancer specific T cell replication, although this also occurs within the ...
The included cancer types are the ones causing most death as per data from the US in 2008. [1] Lung cancer, mainly to adrenal glands, brain, and bone [2] Breast cancer, mainly to bone, liver, lung and brain. [3] Colon cancer, mainly to liver. [4] Pancreatic cancer, mainly to liver and lungs. [5] Melanoma, mainly to brain [6]